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Interrogating accessibility of telomeric sequences with FRET-PAINT: evidence for length-dependent telomere compaction
Single-stranded telomeric overhangs are ∼200 nucleotides long and can form tandem G-quadruplex (GQ) structures, which reduce their accessibility to nucleases and proteins that activate DNA damage response. Whether these tandem GQs further stack to form compact superstructures, which may provide bett...
Autores principales: | Mustafa, Golam, Shiekh, Sajad, GC, Keshav, Abeysirigunawardena, Sanjaya, Balci, Hamza |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034622/ https://www.ncbi.nlm.nih.gov/pubmed/33693934 http://dx.doi.org/10.1093/nar/gkab067 |
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