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Frustrated folding of guanine quadruplexes in telomeric DNA

Human chromosomes terminate in long, single-stranded, DNA overhangs of the repetitive sequence (TTAGGG)n. Sets of four adjacent TTAGGG repeats can fold into guanine quadruplexes (GQ), four-stranded structures that are implicated in telomere maintenance and cell immortalization and are targets in can...

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Detalles Bibliográficos
Autores principales:	Carrino, Simone, Hennecker, Christopher D, Murrieta, Ana C, Mittermaier, Anthony
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034632/ https://www.ncbi.nlm.nih.gov/pubmed/33693924 http://dx.doi.org/10.1093/nar/gkab140

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