Anti-CRISPR AcrIF9 functions by inducing the CRISPR–Cas complex to bind DNA non-specifically

Phages and other mobile genetic elements express anti-CRISPR proteins (Acrs) to protect their genomes from destruction by CRISPR–Cas systems. Acrs usually block the ability of CRISPR–Cas systems to bind or cleave their nucleic acid substrates. Here, we investigate an unusual Acr, AcrIF9, that induce...

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Detalles Bibliográficos
Autores principales: Lu, Wang-Ting, Trost, Chantel N, Müller-Esparza, Hanna, Randau, Lennart, Davidson, Alan R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034650/
https://www.ncbi.nlm.nih.gov/pubmed/33660777
http://dx.doi.org/10.1093/nar/gkab092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034650/
https://www.ncbi.nlm.nih.gov/pubmed/33660777
http://dx.doi.org/10.1093/nar/gkab092

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