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Unraveling the interaction between doxorubicin and DNA origami nanostructures for customizable chemotherapeutic drug release
Doxorubicin (DOX) is a common drug in cancer chemotherapy, and its high DNA-binding affinity can be harnessed in preparing DOX-loaded DNA nanostructures for targeted delivery and therapeutics. Although DOX has been widely studied, the existing literature of DOX-loaded DNA-carriers remains limited an...
Autores principales: | Ijäs, Heini, Shen, Boxuan, Heuer-Jungemann, Amelie, Keller, Adrian, Kostiainen, Mauri A, Liedl, Tim, Ihalainen, Janne A, Linko, Veikko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034656/ https://www.ncbi.nlm.nih.gov/pubmed/33660776 http://dx.doi.org/10.1093/nar/gkab097 |
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