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Comprehensive mutagenesis identifies the peptide repertoire of a p53 T-cell receptor mimic antibody that displays no toxicity in mice transgenic for human HLA-A*0201

T-cell receptor mimic (TCRm) antibodies have expanded the repertoire of antigens targetable by monoclonal antibodies, to include peptides derived from intracellular proteins that are presented by major histocompatibility complex class I (MHC-I) molecules on the cell surface. We have previously used...

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Detalles Bibliográficos
Autores principales:	Trenevska, Iva, Anderson, Amanda P., Bentley, Carol, Hassanali, Tasneem, Wiblin, Sarah, Maguire, Shaun, Pezzella, Francesco, Banham, Alison H., Li, Demin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034716/ https://www.ncbi.nlm.nih.gov/pubmed/33836029 http://dx.doi.org/10.1371/journal.pone.0249967

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