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Androgens regulate ovarian gene expression by balancing Ezh2-Jmjd3 mediated H3K27me3 dynamics
Conventionally viewed as male hormone, androgens play a critical role in female fertility. Although androgen receptors (AR) are transcription factors, to date very few direct transcriptional targets of ARs have been identified in the ovary. Using mouse models, this study provides three critical insi...
Autores principales: | Roy, Sambit, Huang, Binbin, Sinha, Niharika, Wang, Jianrong, Sen, Aritro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034747/ https://www.ncbi.nlm.nih.gov/pubmed/33784295 http://dx.doi.org/10.1371/journal.pgen.1009483 |
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