The effect of calcium in water hardness on digoxin plasma levels in an experimental rat model

BACKGROUND: Digoxin is a drug for ventricular rate control in atrial fibrillation (AF). The major challenge in digoxin therapy is to adjust the appropriate concentration range for this drug due to its narrow therapeutic index. Unique physiochemical properties of drinking water affect the pharmacolog...

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Detalles Bibliográficos
Autores principales: Shahsavand, Shabnam, Moshirfar, Mohammad, Seyed-Sharifi, Seyed Hassan, Younessi-Heravi, Mohammad Amin, Ghasemi, Reza, Valaei, Morteza, Yaghubi, Mohsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034760/
https://www.ncbi.nlm.nih.gov/pubmed/33889190
http://dx.doi.org/10.22122/arya.v16i5.2112

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