Cargando…

Intraobserver and interobserver variations in cortical transit time measurement in children with pelviureteric junction obstruction

Cortical transit time (CTT) has recently been shown to be a useful parameter in the management of children with pelviureteric junction obstruction (PUJO). The aim of this study was to assess intraobserver and interobserver variations in the qualitative and quantitative assessment of CTT in children...

Descripción completa

Detalles Bibliográficos
Autores principales: Jain, Vishesh, Kumar, Rakesh, Shamim, Shamim Ahmed, Arora, Saurabh, Mani, Kalaivani, Yadav, Devendra Kumar, Goel, Prabudh, Dhua, Anjan, Agarwala, Sandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034798/
https://www.ncbi.nlm.nih.gov/pubmed/33850488
http://dx.doi.org/10.4103/wjnm.WJNM_37_20
_version_ 1783676602855456768
author Jain, Vishesh
Kumar, Rakesh
Shamim, Shamim Ahmed
Arora, Saurabh
Mani, Kalaivani
Yadav, Devendra Kumar
Goel, Prabudh
Dhua, Anjan
Agarwala, Sandeep
author_facet Jain, Vishesh
Kumar, Rakesh
Shamim, Shamim Ahmed
Arora, Saurabh
Mani, Kalaivani
Yadav, Devendra Kumar
Goel, Prabudh
Dhua, Anjan
Agarwala, Sandeep
author_sort Jain, Vishesh
collection PubMed
description Cortical transit time (CTT) has recently been shown to be a useful parameter in the management of children with pelviureteric junction obstruction (PUJO). The aim of this study was to assess intraobserver and interobserver variations in the qualitative and quantitative assessment of CTT in children with PUJO. A retrospective study was performed, and (99m)Tc-MAG3 renogram images of all children with PUJO performed from January 2016 to December 2017 were retrieved. The images were assessed by three observers at two different time points. CTT was qualified as delayed if CTT was more than 3 min else; it was noted as normal. The intraobserver and interobserver variations in the results of the CTT of the normal kidney and affected kidney both before and after surgery were studied. The kappa statistic was used to compare the interobserver variation of qualitative interpretation of CTT. The Bland–Altman plot was used to evaluate the intraobserver and interobserver variations of the quantitative interpretation of CTT. A total of 57 (99m)Tc-MAG3 renal scintigraphies were evaluated. Overall, 114 renal units were evaluated with 51 normal renal units and 63 renal units with PUJO. Of these, 63 renal units with PUJO, 31 renal units had been operated upon, whereas the remaining 32 renal units had no intervention at the time of the study. The kappa statistic in the normal, affected operated, and affected unoperated kidneys was interpreted as almost perfect, substantial to almost perfect, and moderate to substantial level of agreement, respectively. The Bland–Altman plot revealed a large mean difference and wide 95% limits of agreement in affected kidneys (both operated and unoperated). The study concludes that the qualitative CTT interpretation in the affected renal unit which is most commonly used in recent studies is a reliable and reproducible parameter in children with PUJO. The quantitative measurement had wide inter- and intraobserver variation for clinical use.
format Online
Article
Text
id pubmed-8034798
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-80347982021-04-12 Intraobserver and interobserver variations in cortical transit time measurement in children with pelviureteric junction obstruction Jain, Vishesh Kumar, Rakesh Shamim, Shamim Ahmed Arora, Saurabh Mani, Kalaivani Yadav, Devendra Kumar Goel, Prabudh Dhua, Anjan Agarwala, Sandeep World J Nucl Med Original Article Cortical transit time (CTT) has recently been shown to be a useful parameter in the management of children with pelviureteric junction obstruction (PUJO). The aim of this study was to assess intraobserver and interobserver variations in the qualitative and quantitative assessment of CTT in children with PUJO. A retrospective study was performed, and (99m)Tc-MAG3 renogram images of all children with PUJO performed from January 2016 to December 2017 were retrieved. The images were assessed by three observers at two different time points. CTT was qualified as delayed if CTT was more than 3 min else; it was noted as normal. The intraobserver and interobserver variations in the results of the CTT of the normal kidney and affected kidney both before and after surgery were studied. The kappa statistic was used to compare the interobserver variation of qualitative interpretation of CTT. The Bland–Altman plot was used to evaluate the intraobserver and interobserver variations of the quantitative interpretation of CTT. A total of 57 (99m)Tc-MAG3 renal scintigraphies were evaluated. Overall, 114 renal units were evaluated with 51 normal renal units and 63 renal units with PUJO. Of these, 63 renal units with PUJO, 31 renal units had been operated upon, whereas the remaining 32 renal units had no intervention at the time of the study. The kappa statistic in the normal, affected operated, and affected unoperated kidneys was interpreted as almost perfect, substantial to almost perfect, and moderate to substantial level of agreement, respectively. The Bland–Altman plot revealed a large mean difference and wide 95% limits of agreement in affected kidneys (both operated and unoperated). The study concludes that the qualitative CTT interpretation in the affected renal unit which is most commonly used in recent studies is a reliable and reproducible parameter in children with PUJO. The quantitative measurement had wide inter- and intraobserver variation for clinical use. Wolters Kluwer - Medknow 2020-09-14 /pmc/articles/PMC8034798/ /pubmed/33850488 http://dx.doi.org/10.4103/wjnm.WJNM_37_20 Text en Copyright: © 2020 World Journal of Nuclear Medicine https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Jain, Vishesh
Kumar, Rakesh
Shamim, Shamim Ahmed
Arora, Saurabh
Mani, Kalaivani
Yadav, Devendra Kumar
Goel, Prabudh
Dhua, Anjan
Agarwala, Sandeep
Intraobserver and interobserver variations in cortical transit time measurement in children with pelviureteric junction obstruction
title Intraobserver and interobserver variations in cortical transit time measurement in children with pelviureteric junction obstruction
title_full Intraobserver and interobserver variations in cortical transit time measurement in children with pelviureteric junction obstruction
title_fullStr Intraobserver and interobserver variations in cortical transit time measurement in children with pelviureteric junction obstruction
title_full_unstemmed Intraobserver and interobserver variations in cortical transit time measurement in children with pelviureteric junction obstruction
title_short Intraobserver and interobserver variations in cortical transit time measurement in children with pelviureteric junction obstruction
title_sort intraobserver and interobserver variations in cortical transit time measurement in children with pelviureteric junction obstruction
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034798/
https://www.ncbi.nlm.nih.gov/pubmed/33850488
http://dx.doi.org/10.4103/wjnm.WJNM_37_20
work_keys_str_mv AT jainvishesh intraobserverandinterobservervariationsincorticaltransittimemeasurementinchildrenwithpelviuretericjunctionobstruction
AT kumarrakesh intraobserverandinterobservervariationsincorticaltransittimemeasurementinchildrenwithpelviuretericjunctionobstruction
AT shamimshamimahmed intraobserverandinterobservervariationsincorticaltransittimemeasurementinchildrenwithpelviuretericjunctionobstruction
AT arorasaurabh intraobserverandinterobservervariationsincorticaltransittimemeasurementinchildrenwithpelviuretericjunctionobstruction
AT manikalaivani intraobserverandinterobservervariationsincorticaltransittimemeasurementinchildrenwithpelviuretericjunctionobstruction
AT yadavdevendrakumar intraobserverandinterobservervariationsincorticaltransittimemeasurementinchildrenwithpelviuretericjunctionobstruction
AT goelprabudh intraobserverandinterobservervariationsincorticaltransittimemeasurementinchildrenwithpelviuretericjunctionobstruction
AT dhuaanjan intraobserverandinterobservervariationsincorticaltransittimemeasurementinchildrenwithpelviuretericjunctionobstruction
AT agarwalasandeep intraobserverandinterobservervariationsincorticaltransittimemeasurementinchildrenwithpelviuretericjunctionobstruction