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Ketogenic diet reduces alcohol withdrawal symptoms in humans and alcohol intake in rodents

Individuals with alcohol use disorder (AUD) show elevated brain metabolism of acetate at the expense of glucose. We hypothesized that a shift in energy substrates during withdrawal may contribute to withdrawal severity and neurotoxicity in AUD and that a ketogenic diet (KD) may mitigate these effect...

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Detalles Bibliográficos
Autores principales: Wiers, Corinde E., Vendruscolo, Leandro F., van der Veen, Jan-Willem, Manza, Peter, Shokri-Kojori, Ehsan, Kroll, Danielle S., Feldman, Dana E., McPherson, Katherine L., Biesecker, Catherine L., Zhang, Rui, Herman, Kimberly, Elvig, Sophie K., Vendruscolo, Janaina C. M., Turner, Sara A., Yang, Shanna, Schwandt, Melanie, Tomasi, Dardo, Cervenka, Mackenzie C., Fink-Jensen, Anders, Benveniste, Helene, Diazgranados, Nancy, Wang, Gene-Jack, Koob, George F., Volkow, Nora D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034849/
https://www.ncbi.nlm.nih.gov/pubmed/33837086
http://dx.doi.org/10.1126/sciadv.abf6780

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