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HDAC11 inhibition disrupts porcine oocyte meiosis via regulating α-tubulin acetylation and histone modifications

HDAC11, the sole member of HDAC class IV family, plays vital roles in activating mitosis and apoptosis of tumor cells, but its functions in meiosis are rarely investigated. In the present study, the effect of HDAC11 on meiosis during porcine oocytes maturation was fully studied. The results showed t...

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Detalles Bibliográficos
Autores principales: Huang, Rong, Sui, Liyan, Fu, Cong, Zhai, Yanhui, Dai, Xiangpeng, Zhang, Sheng, Li, Ziyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034937/
https://www.ncbi.nlm.nih.gov/pubmed/33742608
http://dx.doi.org/10.18632/aging.202697

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