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Classification and Design of HIV-1 Integrase Inhibitors Based on Machine Learning

A key enzyme in human immunodeficiency virus type 1 (HIV-1) life cycle, integrase (IN) aids the integration of viral DNA into the host DNA, which has become an ideal target for the development of anti-HIV drugs. A total of 1785 potential HIV-1 IN inhibitors were collected from the databases of ChEMB...

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Detalles Bibliográficos
Autores principales:	Zhou, Junlin, Hao, Juan, Peng, Lianxin, Duan, Huaichuan, Luo, Qing, Yan, Hailian, Wan, Hua, Hu, Yichen, Liang, Li, Xie, Zhenjian, Liu, Wei, Zhao, Gang, Hu, Jianping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035010/ https://www.ncbi.nlm.nih.gov/pubmed/33868450 http://dx.doi.org/10.1155/2021/5559338

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