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Serum-derived exosomal PD-L1 expression to predict anti-PD-1 response and in patients with non-small cell lung cancer

PD-L1 expression is the most useful predictive biomarker for immunotherapy efficacy on non-small cell lung cancer (NSCLC), and CD8+ tumor-infiltrating lymphocytes (CD8+ TILs) play an essential role in the clinical activity of immunotherapy. PD-L1 is found on the exosome’s surface, and PD-L1 expressi...

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Detalles Bibliográficos
Autores principales:	Shimada, Yoshihisa, Matsubayashi, Jun, Kudo, Yujin, Maehara, Sachio, Takeuchi, Susumu, Hagiwara, Masaru, Kakihana, Masatoshi, Ohira, Tatsuo, Nagao, Toshitaka, Ikeda, Norihiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035184/ https://www.ncbi.nlm.nih.gov/pubmed/33837261 http://dx.doi.org/10.1038/s41598-021-87575-3

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