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GCG inhibits SARS-CoV-2 replication by disrupting the liquid phase condensation of its nucleocapsid protein

Lack of detailed knowledge of SARS-CoV-2 infection has been hampering the development of treatments for coronavirus disease 2019 (COVID-19). Here, we report that RNA triggers the liquid–liquid phase separation (LLPS) of the SARS-CoV-2 nucleocapsid protein, N. By analyzing all 29 proteins of SARS-CoV...

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Detalles Bibliográficos
Autores principales:	Zhao, Ming, Yu, Yu, Sun, Li-Ming, Xing, Jia-Qing, Li, Tingting, Zhu, Yunkai, Wang, Miao, Yu, Yin, Xue, Wen, Xia, Tian, Cai, Hong, Han, Qiu-Ying, Yin, Xiaoyao, Li, Wei-Hua, Li, Ai-Ling, Cui, Jiuwei, Yuan, Zhenghong, Zhang, Rong, Zhou, Tao, Zhang, Xue-Min, Li, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035206/ https://www.ncbi.nlm.nih.gov/pubmed/33837182 http://dx.doi.org/10.1038/s41467-021-22297-8

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