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Characterization of clostridium botulinum neurotoxin serotype A (BoNT/A) and fibroblast growth factor receptor interactions using novel receptor dimerization assay
Clostridium botulinum neurotoxin serotype A (BoNT/A) is a potent neurotoxin that serves as an effective therapeutic for several neuromuscular disorders via induction of temporary muscular paralysis. Specific binding and internalization of BoNT/A into neuronal cells is mediated by its binding domain...
Autores principales: | James, Nicholas G., Malik, Shiazah, Sanstrum, Bethany J., Rhéaume, Catherine, Broide, Ron S., Jameson, David M., Brideau-Andersen, Amy, Jacky, Birgitte S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035261/ https://www.ncbi.nlm.nih.gov/pubmed/33837264 http://dx.doi.org/10.1038/s41598-021-87331-7 |
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