Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunity

Mito-SEPs are small open reading frame-encoded peptides that localize to the mitochondria to regulate metabolism. Motivated by an intriguing negative association between mito-SEPs and inflammation, here we screen for mito-SEPs that modify inflammatory outcomes and report a mito-SEP named “Modulator...

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Detalles Bibliográficos
Autores principales: Lee, Cheryl Q. E., Kerouanton, Baptiste, Chothani, Sonia, Zhang, Shan, Chen, Ying, Mantri, Chinmay Kumar, Hock, Daniella Helena, Lim, Radiance, Nadkarni, Rhea, Huynh, Vinh Thang, Lim, Daryl, Chew, Wei Leong, Zhong, Franklin L., Stroud, David Arthur, Schafer, Sebastian, Tergaonkar, Vinay, St John, Ashley L., Rackham, Owen J. L., Ho, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035321/
https://www.ncbi.nlm.nih.gov/pubmed/33837217
http://dx.doi.org/10.1038/s41467-021-22397-5

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