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T cell reactivity to regulatory factor X4 in type 1 narcolepsy

Type 1 narcolepsy is strongly (98%) associated with human leukocyte antigen (HLA) class II DQA1*01:02/DQB1*06:02 (DQ0602) and highly associated with T cell receptor (TCR) alpha locus polymorphism as well as other immune regulatory loci. Increased incidence of narcolepsy was detected following the 20...

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Detalles Bibliográficos
Autores principales: Luo, Guo, Yogeshwar, Selina, Lin, Ling, Mignot, Emmanuel Jean-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035403/
https://www.ncbi.nlm.nih.gov/pubmed/33837283
http://dx.doi.org/10.1038/s41598-021-87481-8