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Is gastric mapping needed in the endoscopy of dyspeptic patients?

AIM: Our study aimed to determine the prevalence of intestinal metaplasia in dyspeptic patients who underwent upper GI endoscopy. BACKGROUND: Intestinal metaplasia, which is defined as the replacement of normal gastric mucosa by metaplastic intestinal epithelium, has been described as a premalignant...

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Autores principales: Valizadeh Toosi, Seyed Mohammad, Sanayifar, Seyede Fateme, Mohammadpour, Reza Ali, Sheidaei, Somayeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035538/
https://www.ncbi.nlm.nih.gov/pubmed/33868607
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author Valizadeh Toosi, Seyed Mohammad
Sanayifar, Seyede Fateme
Mohammadpour, Reza Ali
Sheidaei, Somayeh
author_facet Valizadeh Toosi, Seyed Mohammad
Sanayifar, Seyede Fateme
Mohammadpour, Reza Ali
Sheidaei, Somayeh
author_sort Valizadeh Toosi, Seyed Mohammad
collection PubMed
description AIM: Our study aimed to determine the prevalence of intestinal metaplasia in dyspeptic patients who underwent upper GI endoscopy. BACKGROUND: Intestinal metaplasia, which is defined as the replacement of normal gastric mucosa by metaplastic intestinal epithelium, has been described as a premalignant gastric lesion. METHODS: Six hundred two consecutive patients with dyspeptic symptoms who had undergone upper GI endoscopy were included in the study. For all patients, gastric mapping was performed to determine the presence of intestinal metaplasia. All histologic samples were reported according to the updated Sydney classification. RESULTS: Total of 61.3% of the patients were female. The mean age of the patients was 46±15 years. The overall prevalence of intestinal metaplasia was 22%. The distribution of intestinal metaplasia in the stomach was 15.1% in the antrum, 4.3% in the body, and 2.6% in the antrum and body together. Also, the prevalence of intestinal metaplasia in the age group of under 40 years was 9.5% and in patients over 40 years it was 29.5%.. CONCLUSION: The results of this study have shown that more than one-fifth of the patients with dyspepsia have intestinal metaplasia. This indicates that gastric mapping in patients with dyspepsia may lead to the detection of precancerous lesions especially after the age of 40.
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spelling pubmed-80355382021-04-16 Is gastric mapping needed in the endoscopy of dyspeptic patients? Valizadeh Toosi, Seyed Mohammad Sanayifar, Seyede Fateme Mohammadpour, Reza Ali Sheidaei, Somayeh Gastroenterol Hepatol Bed Bench Research Article AIM: Our study aimed to determine the prevalence of intestinal metaplasia in dyspeptic patients who underwent upper GI endoscopy. BACKGROUND: Intestinal metaplasia, which is defined as the replacement of normal gastric mucosa by metaplastic intestinal epithelium, has been described as a premalignant gastric lesion. METHODS: Six hundred two consecutive patients with dyspeptic symptoms who had undergone upper GI endoscopy were included in the study. For all patients, gastric mapping was performed to determine the presence of intestinal metaplasia. All histologic samples were reported according to the updated Sydney classification. RESULTS: Total of 61.3% of the patients were female. The mean age of the patients was 46±15 years. The overall prevalence of intestinal metaplasia was 22%. The distribution of intestinal metaplasia in the stomach was 15.1% in the antrum, 4.3% in the body, and 2.6% in the antrum and body together. Also, the prevalence of intestinal metaplasia in the age group of under 40 years was 9.5% and in patients over 40 years it was 29.5%.. CONCLUSION: The results of this study have shown that more than one-fifth of the patients with dyspepsia have intestinal metaplasia. This indicates that gastric mapping in patients with dyspepsia may lead to the detection of precancerous lesions especially after the age of 40. Shaheed Beheshti University of Medical Sciences 2021 /pmc/articles/PMC8035538/ /pubmed/33868607 Text en ©2021 RIGLD, Research Institute for Gastroenterology and Liver Diseases https://creativecommons.org/licenses/by/3.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/ (https://creativecommons.org/licenses/by/3.0/) ) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Valizadeh Toosi, Seyed Mohammad
Sanayifar, Seyede Fateme
Mohammadpour, Reza Ali
Sheidaei, Somayeh
Is gastric mapping needed in the endoscopy of dyspeptic patients?
title Is gastric mapping needed in the endoscopy of dyspeptic patients?
title_full Is gastric mapping needed in the endoscopy of dyspeptic patients?
title_fullStr Is gastric mapping needed in the endoscopy of dyspeptic patients?
title_full_unstemmed Is gastric mapping needed in the endoscopy of dyspeptic patients?
title_short Is gastric mapping needed in the endoscopy of dyspeptic patients?
title_sort is gastric mapping needed in the endoscopy of dyspeptic patients?
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035538/
https://www.ncbi.nlm.nih.gov/pubmed/33868607
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