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2,5-Hexanedione induced apoptosis in rat spinal cord neurons and VSC4.1 cells via the proNGF/p75NTR and JNK pathways

Increasing evidence suggests that n-hexane induces nerve injury via neuronal apoptosis induced by its active metabolite 2,5-hexanedione (HD). However, the underlying mechanism remains unknown. Studies have confirmed that pro-nerve growth factor (proNGF), a precursor of mature nerve growth factor (mN...

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Detalles Bibliográficos
Autores principales:	Luo, Mengxin, Shi, Xiaoxia, Guo, Qi, Li, Shuangyue, Zhang, Qing, Sun, Xiuyan, Piao, Fengyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2021
Materias:	Cell Death & Injury
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035625/ https://www.ncbi.nlm.nih.gov/pubmed/33792642 http://dx.doi.org/10.1042/BSR20204264

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