Cathepsin S Cleaves BAX as a Novel and Therapeutically Important Regulatory Mechanism for Apoptosis

Certain lysosomal cathepsin proteins have come into focus as being good candidates for therapeutic targeting, based on them being over-expressed in a variety of cancers and based on their regulation of the apoptotic pathway. Here, we report novel findings that highlight the ability of cathepsin S ex...

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Detalles Bibliográficos
Autores principales: Soond, Surinder M., Savvateeva, Lyudmila V., Makarov, Vladimir A., Gorokhovets, Neonila V., Townsend, Paul A., Zamyatnin, Andrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035670/
https://www.ncbi.nlm.nih.gov/pubmed/33807987
http://dx.doi.org/10.3390/pharmaceutics13030339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035670/
https://www.ncbi.nlm.nih.gov/pubmed/33807987
http://dx.doi.org/10.3390/pharmaceutics13030339

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