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Cathepsin S Cleaves BAX as a Novel and Therapeutically Important Regulatory Mechanism for Apoptosis
Certain lysosomal cathepsin proteins have come into focus as being good candidates for therapeutic targeting, based on them being over-expressed in a variety of cancers and based on their regulation of the apoptotic pathway. Here, we report novel findings that highlight the ability of cathepsin S ex...
Autores principales: | Soond, Surinder M., Savvateeva, Lyudmila V., Makarov, Vladimir A., Gorokhovets, Neonila V., Townsend, Paul A., Zamyatnin, Andrey A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035670/ https://www.ncbi.nlm.nih.gov/pubmed/33807987 http://dx.doi.org/10.3390/pharmaceutics13030339 |
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