Cargando…

Thyrotoxic Periodic Paralysis with Thyroid Storm as the First Presentation of Graves’ disease; a Case Report

Thyrotoxic periodic paralysis is a rare endocrine emergency that manifests as acute onset muscle weakness and hypokalaemia secondary to thyrotoxicosis. It mainly occurs due to rapid and dramatic intracellular shift of potassium resulting in hypokalaemia and acute flaccid paralysis. This condition pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Banavathu, Tejaswee, Tripathi, Swapnil, Sukhadiya, Pankaj, Ahari, Kamlesh, Meena, Durga Shankar, Garg, Mahendra Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shahid Beheshti University of Medical Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035699/
https://www.ncbi.nlm.nih.gov/pubmed/33870206
http://dx.doi.org/10.22037/aaem.v9i1.1083
_version_ 1783676756006273024
author Banavathu, Tejaswee
Tripathi, Swapnil
Sukhadiya, Pankaj
Ahari, Kamlesh
Meena, Durga Shankar
Garg, Mahendra Kumar
author_facet Banavathu, Tejaswee
Tripathi, Swapnil
Sukhadiya, Pankaj
Ahari, Kamlesh
Meena, Durga Shankar
Garg, Mahendra Kumar
author_sort Banavathu, Tejaswee
collection PubMed
description Thyrotoxic periodic paralysis is a rare endocrine emergency that manifests as acute onset muscle weakness and hypokalaemia secondary to thyrotoxicosis. It mainly occurs due to rapid and dramatic intracellular shift of potassium resulting in hypokalaemia and acute flaccid paralysis. This condition predominantly affects males of Asian descent, and presentation can range from mild generalized weakness to complete quadriplegia, as seen in our case. We herein report a case of a 40-year-old female, who presented to us with acute onset flaccid quadriplegia and thyroid storm, which is the first ever manifestation of previously undiagnosed Grave’s disease. Liver abscess was found to be the underlying trigger for thyrotoxic paralysis and thyroid storm.
format Online
Article
Text
id pubmed-8035699
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Shahid Beheshti University of Medical Sciences
record_format MEDLINE/PubMed
spelling pubmed-80356992021-04-16 Thyrotoxic Periodic Paralysis with Thyroid Storm as the First Presentation of Graves’ disease; a Case Report Banavathu, Tejaswee Tripathi, Swapnil Sukhadiya, Pankaj Ahari, Kamlesh Meena, Durga Shankar Garg, Mahendra Kumar Arch Acad Emerg Med Case Report Thyrotoxic periodic paralysis is a rare endocrine emergency that manifests as acute onset muscle weakness and hypokalaemia secondary to thyrotoxicosis. It mainly occurs due to rapid and dramatic intracellular shift of potassium resulting in hypokalaemia and acute flaccid paralysis. This condition predominantly affects males of Asian descent, and presentation can range from mild generalized weakness to complete quadriplegia, as seen in our case. We herein report a case of a 40-year-old female, who presented to us with acute onset flaccid quadriplegia and thyroid storm, which is the first ever manifestation of previously undiagnosed Grave’s disease. Liver abscess was found to be the underlying trigger for thyrotoxic paralysis and thyroid storm. Shahid Beheshti University of Medical Sciences 2021-02-17 /pmc/articles/PMC8035699/ /pubmed/33870206 http://dx.doi.org/10.22037/aaem.v9i1.1083 Text en https://creativecommons.org/licenses/by/3.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/ (https://creativecommons.org/licenses/by/3.0/) ) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Banavathu, Tejaswee
Tripathi, Swapnil
Sukhadiya, Pankaj
Ahari, Kamlesh
Meena, Durga Shankar
Garg, Mahendra Kumar
Thyrotoxic Periodic Paralysis with Thyroid Storm as the First Presentation of Graves’ disease; a Case Report
title Thyrotoxic Periodic Paralysis with Thyroid Storm as the First Presentation of Graves’ disease; a Case Report
title_full Thyrotoxic Periodic Paralysis with Thyroid Storm as the First Presentation of Graves’ disease; a Case Report
title_fullStr Thyrotoxic Periodic Paralysis with Thyroid Storm as the First Presentation of Graves’ disease; a Case Report
title_full_unstemmed Thyrotoxic Periodic Paralysis with Thyroid Storm as the First Presentation of Graves’ disease; a Case Report
title_short Thyrotoxic Periodic Paralysis with Thyroid Storm as the First Presentation of Graves’ disease; a Case Report
title_sort thyrotoxic periodic paralysis with thyroid storm as the first presentation of graves’ disease; a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035699/
https://www.ncbi.nlm.nih.gov/pubmed/33870206
http://dx.doi.org/10.22037/aaem.v9i1.1083
work_keys_str_mv AT banavathutejaswee thyrotoxicperiodicparalysiswiththyroidstormasthefirstpresentationofgravesdiseaseacasereport
AT tripathiswapnil thyrotoxicperiodicparalysiswiththyroidstormasthefirstpresentationofgravesdiseaseacasereport
AT sukhadiyapankaj thyrotoxicperiodicparalysiswiththyroidstormasthefirstpresentationofgravesdiseaseacasereport
AT aharikamlesh thyrotoxicperiodicparalysiswiththyroidstormasthefirstpresentationofgravesdiseaseacasereport
AT meenadurgashankar thyrotoxicperiodicparalysiswiththyroidstormasthefirstpresentationofgravesdiseaseacasereport
AT gargmahendrakumar thyrotoxicperiodicparalysiswiththyroidstormasthefirstpresentationofgravesdiseaseacasereport