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Effect of Synchronous Versus Sequential Regimens on the Pharmacokinetics and Biodistribution of Regorafenib with Irradiation

This study was performed to evaluate the interaction between conventional or high-dose radiotherapy (RT) and the pharmacokinetics (PK) of regorafenib in concurrent or sequential regimens for the treatment of hepatocellular carcinoma. Concurrent and sequential in vitro and in vivo studies of irradiat...

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Detalles Bibliográficos
Autores principales: Tsai, Tung-Hu, Chen, Yu-Jen, Wang, Li-Ying, Hsieh, Chen-Hsi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035703/
https://www.ncbi.nlm.nih.gov/pubmed/33805831
http://dx.doi.org/10.3390/pharmaceutics13030386