Cargando…
Prediction of 11-year incidence of psychophysically dependent status or death among community-dwelling younger elderlies: from an age-specified community-based cohort study (the NISSIN project)
BACKGROUND: Predicting adverse health events and implementing preventative measures are a necessary challenge. It is important for healthcare planners and policymakers to allocate the limited resource to high-risk persons. Prediction is also important for older individuals, their family members, and...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035719/ https://www.ncbi.nlm.nih.gov/pubmed/33838644 http://dx.doi.org/10.1186/s12199-021-00968-8 |
_version_ | 1783676758797582336 |
---|---|
author | Okabayashi, Satoe Kawamura, Takashi Noma, Hisashi Wakai, Kenji Ando, Masahiko Tsushita, Kazuyo Ohira, Hideki Ukawa, Shigekazu Tamakoshi, Akiko |
author_facet | Okabayashi, Satoe Kawamura, Takashi Noma, Hisashi Wakai, Kenji Ando, Masahiko Tsushita, Kazuyo Ohira, Hideki Ukawa, Shigekazu Tamakoshi, Akiko |
author_sort | Okabayashi, Satoe |
collection | PubMed |
description | BACKGROUND: Predicting adverse health events and implementing preventative measures are a necessary challenge. It is important for healthcare planners and policymakers to allocate the limited resource to high-risk persons. Prediction is also important for older individuals, their family members, and clinicians to prepare mentally and financially. The aim of this study is to develop a prediction model for within 11-year dependent status requiring long-term nursing care or death in older adults for each sex. METHODS: We carried out age-specified cohort study of community dwellers in Nisshin City, Japan. The older adults aged 64 years who underwent medical check-up between 1996 and 2000 were included in the study. The primary outcome was the incidence of the psychophysically dependent status or death or by the end of the year of age 75 years. Univariable logistic regression analyses were performed to assess the associations between candidate predictors and the outcome. Using the variables with p-values less than 0.1, multivariable logistic regression analyses were then performed with backward stepwise elimination to determine the final predictors for the model. RESULTS: Of the 1525 female participants at baseline, 105 had an incidence of the study outcome. The final prediction model consisted of 15 variables, and the c-statistics for predicting the outcome was 0.763 (95% confidence interval [CI] 0.714–0.813). Of the 1548 male participants at baseline, 211 had incidence of the study outcome. The final prediction model consisted of 16 variables, and the c-statistics for predicting the outcome was 0.735 (95% CI 0.699–0.771). CONCLUSIONS: We developed a prediction model for older adults to forecast 11-year incidence of dependent status requiring nursing care or death in each sex. The predictability was fair, but we could not evaluate the external validity of this model. It could be of some help for healthcare planners, policy makers, clinicians, older individuals, and their family members to weigh the priority of support. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12199-021-00968-8. |
format | Online Article Text |
id | pubmed-8035719 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-80357192021-04-12 Prediction of 11-year incidence of psychophysically dependent status or death among community-dwelling younger elderlies: from an age-specified community-based cohort study (the NISSIN project) Okabayashi, Satoe Kawamura, Takashi Noma, Hisashi Wakai, Kenji Ando, Masahiko Tsushita, Kazuyo Ohira, Hideki Ukawa, Shigekazu Tamakoshi, Akiko Environ Health Prev Med Research Article BACKGROUND: Predicting adverse health events and implementing preventative measures are a necessary challenge. It is important for healthcare planners and policymakers to allocate the limited resource to high-risk persons. Prediction is also important for older individuals, their family members, and clinicians to prepare mentally and financially. The aim of this study is to develop a prediction model for within 11-year dependent status requiring long-term nursing care or death in older adults for each sex. METHODS: We carried out age-specified cohort study of community dwellers in Nisshin City, Japan. The older adults aged 64 years who underwent medical check-up between 1996 and 2000 were included in the study. The primary outcome was the incidence of the psychophysically dependent status or death or by the end of the year of age 75 years. Univariable logistic regression analyses were performed to assess the associations between candidate predictors and the outcome. Using the variables with p-values less than 0.1, multivariable logistic regression analyses were then performed with backward stepwise elimination to determine the final predictors for the model. RESULTS: Of the 1525 female participants at baseline, 105 had an incidence of the study outcome. The final prediction model consisted of 15 variables, and the c-statistics for predicting the outcome was 0.763 (95% confidence interval [CI] 0.714–0.813). Of the 1548 male participants at baseline, 211 had incidence of the study outcome. The final prediction model consisted of 16 variables, and the c-statistics for predicting the outcome was 0.735 (95% CI 0.699–0.771). CONCLUSIONS: We developed a prediction model for older adults to forecast 11-year incidence of dependent status requiring nursing care or death in each sex. The predictability was fair, but we could not evaluate the external validity of this model. It could be of some help for healthcare planners, policy makers, clinicians, older individuals, and their family members to weigh the priority of support. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12199-021-00968-8. BioMed Central 2021-04-10 2021 /pmc/articles/PMC8035719/ /pubmed/33838644 http://dx.doi.org/10.1186/s12199-021-00968-8 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Article Okabayashi, Satoe Kawamura, Takashi Noma, Hisashi Wakai, Kenji Ando, Masahiko Tsushita, Kazuyo Ohira, Hideki Ukawa, Shigekazu Tamakoshi, Akiko Prediction of 11-year incidence of psychophysically dependent status or death among community-dwelling younger elderlies: from an age-specified community-based cohort study (the NISSIN project) |
title | Prediction of 11-year incidence of psychophysically dependent status or death among community-dwelling younger elderlies: from an age-specified community-based cohort study (the NISSIN project) |
title_full | Prediction of 11-year incidence of psychophysically dependent status or death among community-dwelling younger elderlies: from an age-specified community-based cohort study (the NISSIN project) |
title_fullStr | Prediction of 11-year incidence of psychophysically dependent status or death among community-dwelling younger elderlies: from an age-specified community-based cohort study (the NISSIN project) |
title_full_unstemmed | Prediction of 11-year incidence of psychophysically dependent status or death among community-dwelling younger elderlies: from an age-specified community-based cohort study (the NISSIN project) |
title_short | Prediction of 11-year incidence of psychophysically dependent status or death among community-dwelling younger elderlies: from an age-specified community-based cohort study (the NISSIN project) |
title_sort | prediction of 11-year incidence of psychophysically dependent status or death among community-dwelling younger elderlies: from an age-specified community-based cohort study (the nissin project) |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035719/ https://www.ncbi.nlm.nih.gov/pubmed/33838644 http://dx.doi.org/10.1186/s12199-021-00968-8 |
work_keys_str_mv | AT okabayashisatoe predictionof11yearincidenceofpsychophysicallydependentstatusordeathamongcommunitydwellingyoungerelderliesfromanagespecifiedcommunitybasedcohortstudythenissinproject AT kawamuratakashi predictionof11yearincidenceofpsychophysicallydependentstatusordeathamongcommunitydwellingyoungerelderliesfromanagespecifiedcommunitybasedcohortstudythenissinproject AT nomahisashi predictionof11yearincidenceofpsychophysicallydependentstatusordeathamongcommunitydwellingyoungerelderliesfromanagespecifiedcommunitybasedcohortstudythenissinproject AT wakaikenji predictionof11yearincidenceofpsychophysicallydependentstatusordeathamongcommunitydwellingyoungerelderliesfromanagespecifiedcommunitybasedcohortstudythenissinproject AT andomasahiko predictionof11yearincidenceofpsychophysicallydependentstatusordeathamongcommunitydwellingyoungerelderliesfromanagespecifiedcommunitybasedcohortstudythenissinproject AT tsushitakazuyo predictionof11yearincidenceofpsychophysicallydependentstatusordeathamongcommunitydwellingyoungerelderliesfromanagespecifiedcommunitybasedcohortstudythenissinproject AT ohirahideki predictionof11yearincidenceofpsychophysicallydependentstatusordeathamongcommunitydwellingyoungerelderliesfromanagespecifiedcommunitybasedcohortstudythenissinproject AT ukawashigekazu predictionof11yearincidenceofpsychophysicallydependentstatusordeathamongcommunitydwellingyoungerelderliesfromanagespecifiedcommunitybasedcohortstudythenissinproject AT tamakoshiakiko predictionof11yearincidenceofpsychophysicallydependentstatusordeathamongcommunitydwellingyoungerelderliesfromanagespecifiedcommunitybasedcohortstudythenissinproject |