Central composite design for the development of carvedilol-loaded transdermal ethosomal hydrogel for extended and enhanced anti-hypertensive effect

BACKGROUND: Carvedilol, the anti-hypertensive drug, has poor bioavailability when administered orally. Ethosomes-mediated transdermal delivery is considered a potential route of administration to increase the bioavailability of carvedilol. The central composite design could be used as a tool to opti...

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Detalles Bibliográficos
Autores principales: Amarachinta, Padmanabha Rao, Sharma, Garima, Samed, Noufel, Chettupalli, Ananda Kumar, Alle, Madhusudhan, Kim, Jin-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035747/
https://www.ncbi.nlm.nih.gov/pubmed/33836744
http://dx.doi.org/10.1186/s12951-021-00833-4

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