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Fluorescence artifact correction in the thrombin generation assay: Necessity for correction algorithms in procoagulant samples

INTRODUCTION: The thrombin generation (TG) test is a global hemostasis assay sensitive to procoagulant conditions. However, some TG assays may underestimate elevated TG when the thrombin fluorogenic substrate is depleted or fluorescence is attenuated by the inner filter effect (IFE). OBJECTIVES: We...

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Detalles Bibliográficos
Autores principales:	Chang, William C., Jackson, Joseph W., Machlus, Kellie R., Wolberg, Alisa S., Ovanesov, Mikhail V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles ‐ Thrombosis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035796/ https://www.ncbi.nlm.nih.gov/pubmed/33870030 http://dx.doi.org/10.1002/rth2.12499

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