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Imputing single-cell RNA-seq data by considering cell heterogeneity and prior expression of dropouts
Single-cell RNA sequencing (scRNA-seq) provides a powerful tool to determine expression patterns of thousands of individual cells. However, the analysis of scRNA-seq data remains a computational challenge due to the high technical noise such as the presence of dropout events that lead to a large pro...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035992/ https://www.ncbi.nlm.nih.gov/pubmed/33002136 http://dx.doi.org/10.1093/jmcb/mjaa052 |