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Factors associated with post-electroconvulsive therapy delirium: A retrospective chart review study

Although electroconvulsive therapy (ECT) is generally a safe therapeutic method, unexpected adverse effects, such as post-ECT delirium, may occur. Despite its harmful consequences, there has been little discussion about the predictors of post-ECT delirium. Thus, the current study aimed to clarify th...

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Autores principales: Jo, Young Tak, Joo, Sung Woo, Lee, Jungsun, Joo, Yeon Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036032/
https://www.ncbi.nlm.nih.gov/pubmed/33832062
http://dx.doi.org/10.1097/MD.0000000000024508
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author Jo, Young Tak
Joo, Sung Woo
Lee, Jungsun
Joo, Yeon Ho
author_facet Jo, Young Tak
Joo, Sung Woo
Lee, Jungsun
Joo, Yeon Ho
author_sort Jo, Young Tak
collection PubMed
description Although electroconvulsive therapy (ECT) is generally a safe therapeutic method, unexpected adverse effects, such as post-ECT delirium, may occur. Despite its harmful consequences, there has been little discussion about the predictors of post-ECT delirium. Thus, the current study aimed to clarify the factors associated with post-ECT delirium by reviewing electronic medical records of 268 bitemporal ECT sessions from December 2006 to July 2018 in a university hospital. Demographic and clinical characteristics of sessions involving patients with or without post-ECT delirium were compared. Multiple logistic regression analysis was applied to analyze the correlation between variables and post-ECT delirium. Post-ECT delirium developed in 23 sessions (8.6%). Of all the demographic and clinical variables measured, only etomidate use was significantly different between delirium-positive and delirium-negative groups after Bonferroni correction. The regression model also indicated that etomidate use to be significantly associated with post-ECT delirium. In this study, etomidate was associated with a higher risk of developing post-ECT delirium, an association that appeared unrelated to other possible measured variables. Practitioners should take into account the risk of post-ECT delirium while choosing anesthetics, so as to prevent early discontinuation before sufficient therapeutic gain is achieved.
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spelling pubmed-80360322021-04-13 Factors associated with post-electroconvulsive therapy delirium: A retrospective chart review study Jo, Young Tak Joo, Sung Woo Lee, Jungsun Joo, Yeon Ho Medicine (Baltimore) 5000 Although electroconvulsive therapy (ECT) is generally a safe therapeutic method, unexpected adverse effects, such as post-ECT delirium, may occur. Despite its harmful consequences, there has been little discussion about the predictors of post-ECT delirium. Thus, the current study aimed to clarify the factors associated with post-ECT delirium by reviewing electronic medical records of 268 bitemporal ECT sessions from December 2006 to July 2018 in a university hospital. Demographic and clinical characteristics of sessions involving patients with or without post-ECT delirium were compared. Multiple logistic regression analysis was applied to analyze the correlation between variables and post-ECT delirium. Post-ECT delirium developed in 23 sessions (8.6%). Of all the demographic and clinical variables measured, only etomidate use was significantly different between delirium-positive and delirium-negative groups after Bonferroni correction. The regression model also indicated that etomidate use to be significantly associated with post-ECT delirium. In this study, etomidate was associated with a higher risk of developing post-ECT delirium, an association that appeared unrelated to other possible measured variables. Practitioners should take into account the risk of post-ECT delirium while choosing anesthetics, so as to prevent early discontinuation before sufficient therapeutic gain is achieved. Lippincott Williams & Wilkins 2021-04-09 /pmc/articles/PMC8036032/ /pubmed/33832062 http://dx.doi.org/10.1097/MD.0000000000024508 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/)
spellingShingle 5000
Jo, Young Tak
Joo, Sung Woo
Lee, Jungsun
Joo, Yeon Ho
Factors associated with post-electroconvulsive therapy delirium: A retrospective chart review study
title Factors associated with post-electroconvulsive therapy delirium: A retrospective chart review study
title_full Factors associated with post-electroconvulsive therapy delirium: A retrospective chart review study
title_fullStr Factors associated with post-electroconvulsive therapy delirium: A retrospective chart review study
title_full_unstemmed Factors associated with post-electroconvulsive therapy delirium: A retrospective chart review study
title_short Factors associated with post-electroconvulsive therapy delirium: A retrospective chart review study
title_sort factors associated with post-electroconvulsive therapy delirium: a retrospective chart review study
topic 5000
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036032/
https://www.ncbi.nlm.nih.gov/pubmed/33832062
http://dx.doi.org/10.1097/MD.0000000000024508
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