Can coronavirus disease 2019 (COVID-19) trigger exacerbation of multiple sclerosis? A retrospective study

The effect of coronavirus disease (COVID-19) on the risk of relapse in multiple sclerosis (MS) have been unknown. In this retrospective study of 41 relapsing-remitting MS patients, number of relapses in pre-defined at risk-period (ARP) was compared with the previous two years. During the previous tw...

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Detalles Bibliográficos
Autores principales: Barzegar, Mahdi, Vaheb, Saeed, Mirmosayyeb, Omid, Afshari-Safavi, Alireza, Nehzat, Nasim, Shaygannejad, Vahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2021
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036166/
https://www.ncbi.nlm.nih.gov/pubmed/33979771
http://dx.doi.org/10.1016/j.msard.2021.102947
Descripción
Sumario:The effect of coronavirus disease (COVID-19) on the risk of relapse in multiple sclerosis (MS) have been unknown. In this retrospective study of 41 relapsing-remitting MS patients, number of relapses in pre-defined at risk-period (ARP) was compared with the previous two years. During the previous two years, a total of 32 attacks was reported, which 5 (15.6%) were during the at-risk period. After adjusting for age and sex, there was an increased risk of attack during ARP compared to the previous two years (RR: 2.566, 95%CI: 1.075-6.124, P=0.034). Our preliminary study suggested that COVID-19 can trigger exacerbation of MS.

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