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Successful treatment of PLA(2)R1-antibody positive membranous nephropathy with ocrelizumab

Membranous nephropathy (MN) is a common cause of nephrotic syndrome in adults. The disease is induced by antibodies, which are directed against the podocyte protein phospholipase A(2) receptor 1 (PLA(2)R1-ab) in 80% of cases. B cell depleting treatments, most notably rituximab, a chimeric CD20-antib...

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Detalles Bibliográficos
Autores principales: Schmidt, Tilman, Schulze, Matthias, Harendza, Sigrid, Hoxha, Elion
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036191/
https://www.ncbi.nlm.nih.gov/pubmed/33026632
http://dx.doi.org/10.1007/s40620-020-00874-2