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Exogenous Integrin αIIbβ3 Inhibitors Revisited: Past, Present and Future Applications

The integrin αIIbβ3 is the most abundant integrin on platelets. Upon platelet activation, the integrin changes its conformation (inside-out signalling) and outside-in signalling takes place leading to platelet spreading, platelet aggregation and thrombus formation. Bloodsucking parasites such as mos...

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Detalles Bibliográficos
Autores principales:	van den Kerkhof, Danique L., van der Meijden, Paola E.J., Hackeng, Tilman M., Dijkgraaf, Ingrid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036306/ https://www.ncbi.nlm.nih.gov/pubmed/33806083 http://dx.doi.org/10.3390/ijms22073366

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