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Antibacterial Films Based on Polylactide with the Addition of Quercetin and Poly(Ethylene Glycol)
A series of new films with antibacterial properties has been obtained by means of solvent casting method. Biodegradable materials including polylactide (PLA), quercetin (Q) acting as an antibacterial compound and polyethylene glycol (PEG) acting as a plasticizer have been used in the process. The ef...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036468/ https://www.ncbi.nlm.nih.gov/pubmed/33801625 http://dx.doi.org/10.3390/ma14071643 |
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author | Olewnik-Kruszkowska, Ewa Gierszewska, Magdalena Richert, Agnieszka Grabska-Zielińska, Sylwia Rudawska, Anna Bouaziz, Mohamed |
author_facet | Olewnik-Kruszkowska, Ewa Gierszewska, Magdalena Richert, Agnieszka Grabska-Zielińska, Sylwia Rudawska, Anna Bouaziz, Mohamed |
author_sort | Olewnik-Kruszkowska, Ewa |
collection | PubMed |
description | A series of new films with antibacterial properties has been obtained by means of solvent casting method. Biodegradable materials including polylactide (PLA), quercetin (Q) acting as an antibacterial compound and polyethylene glycol (PEG) acting as a plasticizer have been used in the process. The effect of quercetin as well as the amount of PEG on the structural, thermal, mechanical and antibacterial properties of the obtained materials has been determined. It was found that an addition of quercetin significantly influences thermal stability. It should be stressed that samples containing the studied flavonoid are characterized by a higher Young modulus and elongation at break than materials consisting only of PLA and PEG. Moreover, the introduction of 1% of quercetin grants antibacterial properties to the new materials. Recorded results showed that the amount of plasticizer did not influence the antibacterial properties; it does, however, cause changes in physicochemical properties of the obtained materials. These results prove that quercetin could be used as an antibacterial compound and simultaneously improve mechanical and thermal properties of polylactide-based films. |
format | Online Article Text |
id | pubmed-8036468 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-80364682021-04-12 Antibacterial Films Based on Polylactide with the Addition of Quercetin and Poly(Ethylene Glycol) Olewnik-Kruszkowska, Ewa Gierszewska, Magdalena Richert, Agnieszka Grabska-Zielińska, Sylwia Rudawska, Anna Bouaziz, Mohamed Materials (Basel) Article A series of new films with antibacterial properties has been obtained by means of solvent casting method. Biodegradable materials including polylactide (PLA), quercetin (Q) acting as an antibacterial compound and polyethylene glycol (PEG) acting as a plasticizer have been used in the process. The effect of quercetin as well as the amount of PEG on the structural, thermal, mechanical and antibacterial properties of the obtained materials has been determined. It was found that an addition of quercetin significantly influences thermal stability. It should be stressed that samples containing the studied flavonoid are characterized by a higher Young modulus and elongation at break than materials consisting only of PLA and PEG. Moreover, the introduction of 1% of quercetin grants antibacterial properties to the new materials. Recorded results showed that the amount of plasticizer did not influence the antibacterial properties; it does, however, cause changes in physicochemical properties of the obtained materials. These results prove that quercetin could be used as an antibacterial compound and simultaneously improve mechanical and thermal properties of polylactide-based films. MDPI 2021-03-27 /pmc/articles/PMC8036468/ /pubmed/33801625 http://dx.doi.org/10.3390/ma14071643 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ). |
spellingShingle | Article Olewnik-Kruszkowska, Ewa Gierszewska, Magdalena Richert, Agnieszka Grabska-Zielińska, Sylwia Rudawska, Anna Bouaziz, Mohamed Antibacterial Films Based on Polylactide with the Addition of Quercetin and Poly(Ethylene Glycol) |
title | Antibacterial Films Based on Polylactide with the Addition of Quercetin and Poly(Ethylene Glycol) |
title_full | Antibacterial Films Based on Polylactide with the Addition of Quercetin and Poly(Ethylene Glycol) |
title_fullStr | Antibacterial Films Based on Polylactide with the Addition of Quercetin and Poly(Ethylene Glycol) |
title_full_unstemmed | Antibacterial Films Based on Polylactide with the Addition of Quercetin and Poly(Ethylene Glycol) |
title_short | Antibacterial Films Based on Polylactide with the Addition of Quercetin and Poly(Ethylene Glycol) |
title_sort | antibacterial films based on polylactide with the addition of quercetin and poly(ethylene glycol) |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036468/ https://www.ncbi.nlm.nih.gov/pubmed/33801625 http://dx.doi.org/10.3390/ma14071643 |
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