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Antibacterial Films Based on Polylactide with the Addition of Quercetin and Poly(Ethylene Glycol)

A series of new films with antibacterial properties has been obtained by means of solvent casting method. Biodegradable materials including polylactide (PLA), quercetin (Q) acting as an antibacterial compound and polyethylene glycol (PEG) acting as a plasticizer have been used in the process. The ef...

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Autores principales: Olewnik-Kruszkowska, Ewa, Gierszewska, Magdalena, Richert, Agnieszka, Grabska-Zielińska, Sylwia, Rudawska, Anna, Bouaziz, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036468/
https://www.ncbi.nlm.nih.gov/pubmed/33801625
http://dx.doi.org/10.3390/ma14071643
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author Olewnik-Kruszkowska, Ewa
Gierszewska, Magdalena
Richert, Agnieszka
Grabska-Zielińska, Sylwia
Rudawska, Anna
Bouaziz, Mohamed
author_facet Olewnik-Kruszkowska, Ewa
Gierszewska, Magdalena
Richert, Agnieszka
Grabska-Zielińska, Sylwia
Rudawska, Anna
Bouaziz, Mohamed
author_sort Olewnik-Kruszkowska, Ewa
collection PubMed
description A series of new films with antibacterial properties has been obtained by means of solvent casting method. Biodegradable materials including polylactide (PLA), quercetin (Q) acting as an antibacterial compound and polyethylene glycol (PEG) acting as a plasticizer have been used in the process. The effect of quercetin as well as the amount of PEG on the structural, thermal, mechanical and antibacterial properties of the obtained materials has been determined. It was found that an addition of quercetin significantly influences thermal stability. It should be stressed that samples containing the studied flavonoid are characterized by a higher Young modulus and elongation at break than materials consisting only of PLA and PEG. Moreover, the introduction of 1% of quercetin grants antibacterial properties to the new materials. Recorded results showed that the amount of plasticizer did not influence the antibacterial properties; it does, however, cause changes in physicochemical properties of the obtained materials. These results prove that quercetin could be used as an antibacterial compound and simultaneously improve mechanical and thermal properties of polylactide-based films.
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spelling pubmed-80364682021-04-12 Antibacterial Films Based on Polylactide with the Addition of Quercetin and Poly(Ethylene Glycol) Olewnik-Kruszkowska, Ewa Gierszewska, Magdalena Richert, Agnieszka Grabska-Zielińska, Sylwia Rudawska, Anna Bouaziz, Mohamed Materials (Basel) Article A series of new films with antibacterial properties has been obtained by means of solvent casting method. Biodegradable materials including polylactide (PLA), quercetin (Q) acting as an antibacterial compound and polyethylene glycol (PEG) acting as a plasticizer have been used in the process. The effect of quercetin as well as the amount of PEG on the structural, thermal, mechanical and antibacterial properties of the obtained materials has been determined. It was found that an addition of quercetin significantly influences thermal stability. It should be stressed that samples containing the studied flavonoid are characterized by a higher Young modulus and elongation at break than materials consisting only of PLA and PEG. Moreover, the introduction of 1% of quercetin grants antibacterial properties to the new materials. Recorded results showed that the amount of plasticizer did not influence the antibacterial properties; it does, however, cause changes in physicochemical properties of the obtained materials. These results prove that quercetin could be used as an antibacterial compound and simultaneously improve mechanical and thermal properties of polylactide-based films. MDPI 2021-03-27 /pmc/articles/PMC8036468/ /pubmed/33801625 http://dx.doi.org/10.3390/ma14071643 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Article
Olewnik-Kruszkowska, Ewa
Gierszewska, Magdalena
Richert, Agnieszka
Grabska-Zielińska, Sylwia
Rudawska, Anna
Bouaziz, Mohamed
Antibacterial Films Based on Polylactide with the Addition of Quercetin and Poly(Ethylene Glycol)
title Antibacterial Films Based on Polylactide with the Addition of Quercetin and Poly(Ethylene Glycol)
title_full Antibacterial Films Based on Polylactide with the Addition of Quercetin and Poly(Ethylene Glycol)
title_fullStr Antibacterial Films Based on Polylactide with the Addition of Quercetin and Poly(Ethylene Glycol)
title_full_unstemmed Antibacterial Films Based on Polylactide with the Addition of Quercetin and Poly(Ethylene Glycol)
title_short Antibacterial Films Based on Polylactide with the Addition of Quercetin and Poly(Ethylene Glycol)
title_sort antibacterial films based on polylactide with the addition of quercetin and poly(ethylene glycol)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036468/
https://www.ncbi.nlm.nih.gov/pubmed/33801625
http://dx.doi.org/10.3390/ma14071643
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