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CRISPR-Cas9–Mediated TIM3 Knockout in Human Natural Killer Cells Enhances Growth Inhibitory Effects on Human Glioma Cells

Glioblastoma (GBM) is the most common and aggressive primary malignant brain tumor in adults. Natural Killer (NK) cells are potent cytotoxic effector cells against tumor cells inducing GBM cells; therefore, NK cell based- immunotherapy might be a promising target in GBM. T cell immunoglobulin mucin...

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Detalles Bibliográficos
Autores principales:	Morimoto, Takayuki, Nakazawa, Tsutomu, Matsuda, Ryosuke, Nishimura, Fumihiko, Nakamura, Mitsutoshi, Yamada, Shuichi, Nakagawa, Ichiro, Park, Young-Soo, Tsujimura, Takahiro, Nakase, Hiroyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036491/ https://www.ncbi.nlm.nih.gov/pubmed/33800561 http://dx.doi.org/10.3390/ijms22073489

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