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Granulibacter bethesdensis, a Pathogen from Patients with Chronic Granulomatous Disease, Produces a Penta-Acylated Hypostimulatory Glycero-D-talo-oct-2-ulosonic Acid–Lipid A Glycolipid (Ko-Lipid A)
Granulibacter bethesdensis can infect patients with chronic granulomatous disease, an immunodeficiency caused by reduced phagocyte NADPH oxidase function. Intact G. bethesdensis (Gb) is hypostimulatory compared to Escherichia coli, i.e., cytokine production in human blood requires 10–100 times more...
Autores principales: | Muszyński, Artur, Zarember, Kol A., Heiss, Christian, Shiloach, Joseph, Berg, Lars J., Audley, John, Kozyr, Arina, Greenberg, David E., Holland, Steven M., Malech, Harry L., Azadi, Parastoo, Carlson, Russell W., Gallin, John I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036547/ https://www.ncbi.nlm.nih.gov/pubmed/33804872 http://dx.doi.org/10.3390/ijms22073303 |
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