Cargando…
Chemokine Receptor 5 Antagonism Causes Reduction in Joint Inflammation in a Collagen-Induced Arthritis Mouse Model
Rheumatoid arthritis (RA) is a chronic inflammatory disease mainly affecting the synovial joints. A highly potent antagonist of C-C chemokine receptor 5 (CCR5), maraviroc (MVC), plays an essential role in treating several infectious diseases but has not yet been evaluated for its potential effects o...
Autores principales: | Ansari, Mushtaq A., Nadeem, Ahmed, Bakheet, Saleh A., Attia, Sabry M., Shahid, Mudassar, Alyousef, Faris S., Alswailem, Mohammed A., Alqinyah, Mohammed, Ahmad, Sheikh F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036613/ https://www.ncbi.nlm.nih.gov/pubmed/33805933 http://dx.doi.org/10.3390/molecules26071839 |
Ejemplares similares
-
Rituximab exerts its anti-arthritic effects via inhibiting NF-κB/GM-CSF/iNOS signaling in B cells in a mouse model of collagen-induced arthritis
por: Ansari, Mushtaq A., et al.
Publicado: (2023) -
DAPTA, a C-C Chemokine Receptor 5 (CCR5), Leads to the Downregulation of Notch/NF-κB Signaling and Proinflammatory Mediators in CD40(+) Cells in Experimental Autoimmune Encephalomyelitis Model in SJL/J Mice
por: Alghibiwi, Hanan, et al.
Publicado: (2023) -
The Exposure to Lead (Pb) Exacerbates Immunological Abnormalities in BTBR T(+) Itpr(3tf)/J Mice through the Regulation of Signaling Pathways Relevant to T Cells
por: Assiri, Mohammed A., et al.
Publicado: (2023) -
Upregulation of Inflammatory Mediators in Peripheral Blood CD40(+) Cells in Children with Autism Spectrum Disorder
por: Aldossari, Abdullah A., et al.
Publicado: (2023) -
Correction: Utility of Dexrazoxane for the Attenuation of Epirubicin-Induced Genetic Alterations in Mouse Germ Cells
por: Attia, Sabry M., et al.
Publicado: (2016)