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Mechanisms of Cisplatin-Induced Acute Kidney Injury: Pathological Mechanisms, Pharmacological Interventions, and Genetic Mitigations

SIMPLE SUMMARY: Nephrotoxicity is the dose-limiting factor of cisplatin treatment. Nephrotoxicity is characterized by reduced kidney function. Although an often-reversible condition, effects are notably seen years after treatment with cisplatin has ceased. It has an extensive pathophysiological map....

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Detalles Bibliográficos
Autores principales:	McSweeney, Kristen Renee, Gadanec, Laura Kate, Qaradakhi, Tawar, Ali, Benazir Ashiana, Zulli, Anthony, Apostolopoulos, Vasso
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036620/ https://www.ncbi.nlm.nih.gov/pubmed/33805488 http://dx.doi.org/10.3390/cancers13071572

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