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Niclosamide–Clay Intercalate Coated with Nonionic Polymer for Enhanced Bioavailability toward COVID-19 Treatment

Niclosamide (NIC), a conventional anthelmintic agent, is emerging as a repurposed drug for COVID-19 treatment. However, the clinical efficacy is very limited due to its low oral bioavailability resulting from its poor aqueous solubility. In the present study, a new hybrid drug delivery system made o...

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Detalles Bibliográficos
Autores principales: Yu, Seungjin, Piao, Huiyan, Rejinold, N. Sanoj, Jin, Geunwoo, Choi, Goeun, Choy, Jin-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036780/
https://www.ncbi.nlm.nih.gov/pubmed/33810527
http://dx.doi.org/10.3390/polym13071044