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Niclosamide–Clay Intercalate Coated with Nonionic Polymer for Enhanced Bioavailability toward COVID-19 Treatment
Niclosamide (NIC), a conventional anthelmintic agent, is emerging as a repurposed drug for COVID-19 treatment. However, the clinical efficacy is very limited due to its low oral bioavailability resulting from its poor aqueous solubility. In the present study, a new hybrid drug delivery system made o...
Autores principales: | Yu, Seungjin, Piao, Huiyan, Rejinold, N. Sanoj, Jin, Geunwoo, Choi, Goeun, Choy, Jin-Ho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036780/ https://www.ncbi.nlm.nih.gov/pubmed/33810527 http://dx.doi.org/10.3390/polym13071044 |
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