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Antibacterial Activity and Protection Efficiency of Polyvinyl Butyral Nanofibrous Membrane Containing Thymol Prepared through Vertical Electrospinning

Human safety, health management, and disease transmission prevention have become crucial tasks in the present COVID-19 pandemic situation. Masks are widely available and create a safer and disease transmission–free environment. This study presents a facile method of fabricating masks through electro...

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Autores principales: Lu, Wen-Chi, Chen, Ching-Yi, Cho, Chia-Jung, Venkatesan, Manikandan, Chiang, Wei-Hung, Yu, Yang-Yen, Lee, Chen-Hung, Lee, Rong-Ho, Rwei, Syang-Peng, Kuo, Chi-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036783/
https://www.ncbi.nlm.nih.gov/pubmed/33916011
http://dx.doi.org/10.3390/polym13071122
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author Lu, Wen-Chi
Chen, Ching-Yi
Cho, Chia-Jung
Venkatesan, Manikandan
Chiang, Wei-Hung
Yu, Yang-Yen
Lee, Chen-Hung
Lee, Rong-Ho
Rwei, Syang-Peng
Kuo, Chi-Ching
author_facet Lu, Wen-Chi
Chen, Ching-Yi
Cho, Chia-Jung
Venkatesan, Manikandan
Chiang, Wei-Hung
Yu, Yang-Yen
Lee, Chen-Hung
Lee, Rong-Ho
Rwei, Syang-Peng
Kuo, Chi-Ching
author_sort Lu, Wen-Chi
collection PubMed
description Human safety, health management, and disease transmission prevention have become crucial tasks in the present COVID-19 pandemic situation. Masks are widely available and create a safer and disease transmission–free environment. This study presents a facile method of fabricating masks through electrospinning nontoxic polyvinyl butyral (PVB) polymeric matrix with the antibacterial component Thymol, a natural phenol monoterpene. Based on the results of Japanese Industrial Standards and American Association of Textile Chemists and Colorists methods, the maximum antibacterial value of the mask against Gram-positive and Gram-negative bacteria was 5.6 and 6.4, respectively. Moreover, vertical electrospinning was performed to prepare Thymol/PVB nanofiber masks, and the effects of parameters on the submicron particulate filtration efficiency (PFE), differential pressure, and bacterial filtration efficiency (BFE) were determined. Thorough optimization of the small-diameter nanofiber–based antibacterial mask led to denser accumulation and improved PFE and pressure difference; the mask was thus noted to meet the present pandemic requirements. The as-developed nanofibrous masks have the antibacterial activity suggested by the National Standard of the Republic of China (CNS 14774) for general medical masks. Their BFE reaches 99.4%, with a pressure difference of <5 mmH(2)O/cm(2). The mask can safeguard human health and promote a healthy environment.
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spelling pubmed-80367832021-04-12 Antibacterial Activity and Protection Efficiency of Polyvinyl Butyral Nanofibrous Membrane Containing Thymol Prepared through Vertical Electrospinning Lu, Wen-Chi Chen, Ching-Yi Cho, Chia-Jung Venkatesan, Manikandan Chiang, Wei-Hung Yu, Yang-Yen Lee, Chen-Hung Lee, Rong-Ho Rwei, Syang-Peng Kuo, Chi-Ching Polymers (Basel) Article Human safety, health management, and disease transmission prevention have become crucial tasks in the present COVID-19 pandemic situation. Masks are widely available and create a safer and disease transmission–free environment. This study presents a facile method of fabricating masks through electrospinning nontoxic polyvinyl butyral (PVB) polymeric matrix with the antibacterial component Thymol, a natural phenol monoterpene. Based on the results of Japanese Industrial Standards and American Association of Textile Chemists and Colorists methods, the maximum antibacterial value of the mask against Gram-positive and Gram-negative bacteria was 5.6 and 6.4, respectively. Moreover, vertical electrospinning was performed to prepare Thymol/PVB nanofiber masks, and the effects of parameters on the submicron particulate filtration efficiency (PFE), differential pressure, and bacterial filtration efficiency (BFE) were determined. Thorough optimization of the small-diameter nanofiber–based antibacterial mask led to denser accumulation and improved PFE and pressure difference; the mask was thus noted to meet the present pandemic requirements. The as-developed nanofibrous masks have the antibacterial activity suggested by the National Standard of the Republic of China (CNS 14774) for general medical masks. Their BFE reaches 99.4%, with a pressure difference of <5 mmH(2)O/cm(2). The mask can safeguard human health and promote a healthy environment. MDPI 2021-04-01 /pmc/articles/PMC8036783/ /pubmed/33916011 http://dx.doi.org/10.3390/polym13071122 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lu, Wen-Chi
Chen, Ching-Yi
Cho, Chia-Jung
Venkatesan, Manikandan
Chiang, Wei-Hung
Yu, Yang-Yen
Lee, Chen-Hung
Lee, Rong-Ho
Rwei, Syang-Peng
Kuo, Chi-Ching
Antibacterial Activity and Protection Efficiency of Polyvinyl Butyral Nanofibrous Membrane Containing Thymol Prepared through Vertical Electrospinning
title Antibacterial Activity and Protection Efficiency of Polyvinyl Butyral Nanofibrous Membrane Containing Thymol Prepared through Vertical Electrospinning
title_full Antibacterial Activity and Protection Efficiency of Polyvinyl Butyral Nanofibrous Membrane Containing Thymol Prepared through Vertical Electrospinning
title_fullStr Antibacterial Activity and Protection Efficiency of Polyvinyl Butyral Nanofibrous Membrane Containing Thymol Prepared through Vertical Electrospinning
title_full_unstemmed Antibacterial Activity and Protection Efficiency of Polyvinyl Butyral Nanofibrous Membrane Containing Thymol Prepared through Vertical Electrospinning
title_short Antibacterial Activity and Protection Efficiency of Polyvinyl Butyral Nanofibrous Membrane Containing Thymol Prepared through Vertical Electrospinning
title_sort antibacterial activity and protection efficiency of polyvinyl butyral nanofibrous membrane containing thymol prepared through vertical electrospinning
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036783/
https://www.ncbi.nlm.nih.gov/pubmed/33916011
http://dx.doi.org/10.3390/polym13071122
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