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Quality of Life and Coping in Nonalcoholic Fatty Liver Disease: Influence of Diabetes and Obesity

Our aim was to analyze how type 2 diabetes and obesity influence quality of life (QoL) and coping in patients with nonalcoholic fatty liver disease (NAFLD), and which coping strategies predict diabetic or obese participants’ QoL. QoL (SF-12, CLDQ-NAFLD) and coping strategies (COPE-28) were evaluated...

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Autores principales: Funuyet-Salas, Jesús, Pérez-San-Gregorio, María Ángeles, Martín-Rodríguez, Agustín, Romero-Gómez, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036804/
https://www.ncbi.nlm.nih.gov/pubmed/33800585
http://dx.doi.org/10.3390/ijerph18073503
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author Funuyet-Salas, Jesús
Pérez-San-Gregorio, María Ángeles
Martín-Rodríguez, Agustín
Romero-Gómez, Manuel
author_facet Funuyet-Salas, Jesús
Pérez-San-Gregorio, María Ángeles
Martín-Rodríguez, Agustín
Romero-Gómez, Manuel
author_sort Funuyet-Salas, Jesús
collection PubMed
description Our aim was to analyze how type 2 diabetes and obesity influence quality of life (QoL) and coping in patients with nonalcoholic fatty liver disease (NAFLD), and which coping strategies predict diabetic or obese participants’ QoL. QoL (SF-12, CLDQ-NAFLD) and coping strategies (COPE-28) were evaluated in 307 biopsy-proven NAFLD patients with absence or presence of diabetes or obesity. QoL was compared with normality tables for the general Spanish population. Interactive effects were found in physical functioning (p = 0.008), role-physical (p = 0.016) and activity (p = 0.014). Diabetic patients reported worse scores when they were also obese and vice versa, that is, obese patients scored worse when they were also diabetic. Both diabetic and obese patients had lower QoL than those without metabolic pathology or the general population, and obese patients also reported more passive/avoidance coping. Active coping, positive reframing and acceptance predicted better QoL, while denial, self-blame, self-distraction, disengagement and religion predicted lower QoL. In conclusion, diabetes and obesity were associated with lower QoL in patients with NAFLD. Obesity was also associated with more passive/avoidance coping. Furthermore, passive/avoidance coping strategies predicted lower QoL than active, recommending modification of maladaptive coping strategies in future multidisciplinary NAFLD treatments.
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spelling pubmed-80368042021-04-12 Quality of Life and Coping in Nonalcoholic Fatty Liver Disease: Influence of Diabetes and Obesity Funuyet-Salas, Jesús Pérez-San-Gregorio, María Ángeles Martín-Rodríguez, Agustín Romero-Gómez, Manuel Int J Environ Res Public Health Article Our aim was to analyze how type 2 diabetes and obesity influence quality of life (QoL) and coping in patients with nonalcoholic fatty liver disease (NAFLD), and which coping strategies predict diabetic or obese participants’ QoL. QoL (SF-12, CLDQ-NAFLD) and coping strategies (COPE-28) were evaluated in 307 biopsy-proven NAFLD patients with absence or presence of diabetes or obesity. QoL was compared with normality tables for the general Spanish population. Interactive effects were found in physical functioning (p = 0.008), role-physical (p = 0.016) and activity (p = 0.014). Diabetic patients reported worse scores when they were also obese and vice versa, that is, obese patients scored worse when they were also diabetic. Both diabetic and obese patients had lower QoL than those without metabolic pathology or the general population, and obese patients also reported more passive/avoidance coping. Active coping, positive reframing and acceptance predicted better QoL, while denial, self-blame, self-distraction, disengagement and religion predicted lower QoL. In conclusion, diabetes and obesity were associated with lower QoL in patients with NAFLD. Obesity was also associated with more passive/avoidance coping. Furthermore, passive/avoidance coping strategies predicted lower QoL than active, recommending modification of maladaptive coping strategies in future multidisciplinary NAFLD treatments. MDPI 2021-03-28 /pmc/articles/PMC8036804/ /pubmed/33800585 http://dx.doi.org/10.3390/ijerph18073503 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Article
Funuyet-Salas, Jesús
Pérez-San-Gregorio, María Ángeles
Martín-Rodríguez, Agustín
Romero-Gómez, Manuel
Quality of Life and Coping in Nonalcoholic Fatty Liver Disease: Influence of Diabetes and Obesity
title Quality of Life and Coping in Nonalcoholic Fatty Liver Disease: Influence of Diabetes and Obesity
title_full Quality of Life and Coping in Nonalcoholic Fatty Liver Disease: Influence of Diabetes and Obesity
title_fullStr Quality of Life and Coping in Nonalcoholic Fatty Liver Disease: Influence of Diabetes and Obesity
title_full_unstemmed Quality of Life and Coping in Nonalcoholic Fatty Liver Disease: Influence of Diabetes and Obesity
title_short Quality of Life and Coping in Nonalcoholic Fatty Liver Disease: Influence of Diabetes and Obesity
title_sort quality of life and coping in nonalcoholic fatty liver disease: influence of diabetes and obesity
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036804/
https://www.ncbi.nlm.nih.gov/pubmed/33800585
http://dx.doi.org/10.3390/ijerph18073503
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