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The Long Linker Region of Telomere-Binding Protein TRF2 Is Responsible for Interactions with Lamins

Telomere-binding factor 2 (TRF2) is part of the shelterin protein complex found at chromosome ends. Lamin A/C interacts with TRF2 and influences telomere position. TRF2 has an intrinsically disordered region between the ordered dimerization and DNA-binding domains. This domain is referred to as the...

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Detalles Bibliográficos
Autores principales:	Travina, Aleksandra O., Ilicheva, Nadya V., Mittenberg, Alexey G., Shabelnikov, Sergey V., Kotova, Anastasia V., Podgornaya, Olga I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036907/ https://www.ncbi.nlm.nih.gov/pubmed/33804854 http://dx.doi.org/10.3390/ijms22073293

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