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MAPLE Coatings Embedded with Essential Oil-Conjugated Magnetite for Anti-Biofilm Applications

The present study reports on the development and evaluation of nanostructured composite coatings of polylactic acid (PLA) embedded with iron oxide nanoparticles (Fe(3)O(4)) modified with Eucalyptus (Eucalyptus globulus) essential oil. The co-precipitation method was employed to synthesize the magnet...

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Autores principales: Gherasim, Oana, Popescu, Roxana Cristina, Grumezescu, Valentina, Mogoșanu, George Dan, Mogoantă, Laurențiu, Iordache, Florin, Holban, Alina Maria, Vasile, Bogdan Ștefan, Bîrcă, Alexandra Cătălina, Oprea, Ovidiu-Cristian, Grumezescu, Alexandru Mihai, Andronescu, Ecaterina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036921/
https://www.ncbi.nlm.nih.gov/pubmed/33806228
http://dx.doi.org/10.3390/ma14071612
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author Gherasim, Oana
Popescu, Roxana Cristina
Grumezescu, Valentina
Mogoșanu, George Dan
Mogoantă, Laurențiu
Iordache, Florin
Holban, Alina Maria
Vasile, Bogdan Ștefan
Bîrcă, Alexandra Cătălina
Oprea, Ovidiu-Cristian
Grumezescu, Alexandru Mihai
Andronescu, Ecaterina
author_facet Gherasim, Oana
Popescu, Roxana Cristina
Grumezescu, Valentina
Mogoșanu, George Dan
Mogoantă, Laurențiu
Iordache, Florin
Holban, Alina Maria
Vasile, Bogdan Ștefan
Bîrcă, Alexandra Cătălina
Oprea, Ovidiu-Cristian
Grumezescu, Alexandru Mihai
Andronescu, Ecaterina
author_sort Gherasim, Oana
collection PubMed
description The present study reports on the development and evaluation of nanostructured composite coatings of polylactic acid (PLA) embedded with iron oxide nanoparticles (Fe(3)O(4)) modified with Eucalyptus (Eucalyptus globulus) essential oil. The co-precipitation method was employed to synthesize the magnetite particles conjugated with Eucalyptus natural antibiotic (Fe(3)O(4)@EG), while their composition and microstructure were investigated using grazing incidence X-ray diffraction (GIXRD), Fourier transform infrared spectroscopy (FT-IR), thermogravimetric analysis (TGA), transmission electron microscopy (TEM) and dynamic light scattering (DLS). The matrix-assisted pulsed laser evaporation (MAPLE) technique was further employed to obtain PLA/Fe(3)O(4)@EG thin films. Optimal experimental conditions for laser processing were established by complementary infrared microscopy (IRM) and scanning electron microscopy (SEM) investigations. The in vitro biocompatibility with eukaryote cells was proven using mesenchymal stem cells, while the anti-biofilm efficiency of composite PLA/Fe(3)O(4)@EG coatings was assessed against Gram-negative and Gram-positive pathogens.
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spelling pubmed-80369212021-04-12 MAPLE Coatings Embedded with Essential Oil-Conjugated Magnetite for Anti-Biofilm Applications Gherasim, Oana Popescu, Roxana Cristina Grumezescu, Valentina Mogoșanu, George Dan Mogoantă, Laurențiu Iordache, Florin Holban, Alina Maria Vasile, Bogdan Ștefan Bîrcă, Alexandra Cătălina Oprea, Ovidiu-Cristian Grumezescu, Alexandru Mihai Andronescu, Ecaterina Materials (Basel) Article The present study reports on the development and evaluation of nanostructured composite coatings of polylactic acid (PLA) embedded with iron oxide nanoparticles (Fe(3)O(4)) modified with Eucalyptus (Eucalyptus globulus) essential oil. The co-precipitation method was employed to synthesize the magnetite particles conjugated with Eucalyptus natural antibiotic (Fe(3)O(4)@EG), while their composition and microstructure were investigated using grazing incidence X-ray diffraction (GIXRD), Fourier transform infrared spectroscopy (FT-IR), thermogravimetric analysis (TGA), transmission electron microscopy (TEM) and dynamic light scattering (DLS). The matrix-assisted pulsed laser evaporation (MAPLE) technique was further employed to obtain PLA/Fe(3)O(4)@EG thin films. Optimal experimental conditions for laser processing were established by complementary infrared microscopy (IRM) and scanning electron microscopy (SEM) investigations. The in vitro biocompatibility with eukaryote cells was proven using mesenchymal stem cells, while the anti-biofilm efficiency of composite PLA/Fe(3)O(4)@EG coatings was assessed against Gram-negative and Gram-positive pathogens. MDPI 2021-03-25 /pmc/articles/PMC8036921/ /pubmed/33806228 http://dx.doi.org/10.3390/ma14071612 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Article
Gherasim, Oana
Popescu, Roxana Cristina
Grumezescu, Valentina
Mogoșanu, George Dan
Mogoantă, Laurențiu
Iordache, Florin
Holban, Alina Maria
Vasile, Bogdan Ștefan
Bîrcă, Alexandra Cătălina
Oprea, Ovidiu-Cristian
Grumezescu, Alexandru Mihai
Andronescu, Ecaterina
MAPLE Coatings Embedded with Essential Oil-Conjugated Magnetite for Anti-Biofilm Applications
title MAPLE Coatings Embedded with Essential Oil-Conjugated Magnetite for Anti-Biofilm Applications
title_full MAPLE Coatings Embedded with Essential Oil-Conjugated Magnetite for Anti-Biofilm Applications
title_fullStr MAPLE Coatings Embedded with Essential Oil-Conjugated Magnetite for Anti-Biofilm Applications
title_full_unstemmed MAPLE Coatings Embedded with Essential Oil-Conjugated Magnetite for Anti-Biofilm Applications
title_short MAPLE Coatings Embedded with Essential Oil-Conjugated Magnetite for Anti-Biofilm Applications
title_sort maple coatings embedded with essential oil-conjugated magnetite for anti-biofilm applications
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036921/
https://www.ncbi.nlm.nih.gov/pubmed/33806228
http://dx.doi.org/10.3390/ma14071612
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