A Tale of Ice and Fire: The Dual Role for 17β-Estradiol in Balancing DNA Damage and Genome Integrity

SIMPLE SUMMARY: Paradoxically, although the steroid hormone 17β-estradiol (E2) regulates many aspects of male and female physiology, it is described in the chemical indexes as a carcinogen. By the analysis of the literature, we unveil here a novel concept for which E2 possesses a dual nature for whi...

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Detalles Bibliográficos
Autores principales: Pescatori, Sara, Berardinelli, Francesco, Albanesi, Jacopo, Ascenzi, Paolo, Marino, Maria, Antoccia, Antonio, di Masi, Alessandra, Acconcia, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036963/
https://www.ncbi.nlm.nih.gov/pubmed/33808099
http://dx.doi.org/10.3390/cancers13071583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036963/
https://www.ncbi.nlm.nih.gov/pubmed/33808099
http://dx.doi.org/10.3390/cancers13071583

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