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A Theoretical Approach to Coupling the Epithelial-Mesenchymal Transition (EMT) to Extracellular Matrix (ECM) Stiffness via LOXL2
SIMPLE SUMMARY: Epithelial-mesenchymal transition (EMT) is a key process in cancer progression through which cells weaken their cell-cell adhesion and gain mobility and invasive traits. Besides chemical signaling, recent studies have established the connection of EMT to mechanical microenvironment,...
Autores principales: | Deng, Youyuan, Chakraborty, Priyanka, Jolly, Mohit Kumar, Levine, Herbert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037024/ https://www.ncbi.nlm.nih.gov/pubmed/33807227 http://dx.doi.org/10.3390/cancers13071609 |
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