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Amyloid Structural Changes Studied by Infrared Microspectroscopy in Bigenic Cellular Models of Alzheimer’s Disease

Alzheimer’s disease affects millions of lives worldwide. This terminal disease is characterized by the formation of amyloid aggregates, so-called amyloid oligomers. These oligomers are composed of β-sheet structures, which are believed to be neurotoxic. However, the actual secondary structure that c...

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Detalles Bibliográficos
Autores principales: Paulus, Agnes, Engdahl, Anders, Yang, Yiyi, Boza-Serrano, Antonio, Bachiller, Sara, Torres-Garcia, Laura, Svanbergsson, Alexander, Garcia, Megg G., Gouras, Gunnar K., Li, Jia-Yi, Deierborg, Tomas, Klementieva, Oxana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037084/
https://www.ncbi.nlm.nih.gov/pubmed/33810433
http://dx.doi.org/10.3390/ijms22073430