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The Molecular Basis of Ubiquitin-Conjugating Enzymes (E2s) as a Potential Target for Cancer Therapy

Ubiquitin-conjugating enzymes (E2s) are one of the three enzymes required by the ubiquitin-proteasome pathway to connect activated ubiquitin to target proteins via ubiquitin ligases. E2s determine the connection type of the ubiquitin chains, and different types of ubiquitin chains regulate the stabi...

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Detalles Bibliográficos
Autores principales: Du, Xiaodi, Song, Hongyu, Shen, Nengxing, Hua, Ruiqi, Yang, Guangyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037234/
https://www.ncbi.nlm.nih.gov/pubmed/33810518
http://dx.doi.org/10.3390/ijms22073440

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