The Nucleolar Protein Nucleophosmin Is Physiologically Secreted by Endothelial Cells in Response to Stress Exerting Proangiogenic Activity Both In Vitro and In Vivo

Nucleophosmin (NPM), a nucleolar multifunctional phosphoprotein, acts as a stress sensor in different cell types. NPM can be actively secreted by inflammatory cells, however its biology on endothelium remains unexplored. In this study, we show for the first time that NPM is secreted by human vein en...

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Detalles Bibliográficos
Autores principales: Di Carlo, Anna, Beji, Sara, Palmerio, Silvia, Picozza, Mario, D’Agostino, Marco, Petrozza, Vincenzo, Melchionna, Roberta, Germani, Antonia, Magenta, Alessandra, De Falco, Elena, Avitabile, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037380/
https://www.ncbi.nlm.nih.gov/pubmed/33916025
http://dx.doi.org/10.3390/ijms22073672

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