Cargando…
The Antithrombotic Agent Pterostilbene Interferes with Integrin α(IIb)β(3)-Mediated Inside-Out and Outside-In Signals in Human Platelets
Platelets play a crucial role in the physiology of primary hemostasis and pathological processes such as arterial thrombosis; thus, developing a therapeutic target that prevents platelet activation can reduce arterial thrombosis. Pterostilbene (PTE) has remarkable pharmacological activities, includi...
Autores principales: | Huang, Wei-Chieh, Lin, Kao-Chang, Hsia, Chih-Wei, Hsia, Chih-Hsuan, Chen, Ting-Yu, Bhavan, Periyakali Saravana, Sheu, Joen-Rong, Hou, Shaw-Min |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037547/ https://www.ncbi.nlm.nih.gov/pubmed/33807403 http://dx.doi.org/10.3390/ijms22073643 |
Ejemplares similares
-
Modulation of human platelet activation and in vivo vascular thrombosis by columbianadin: regulation by integrin α(IIb)β(3) inside-out but not outside-in signals
por: Hou, Shaw-Min, et al.
Publicado: (2020) -
Mechanisms of glabridin inhibition of integrin α(IIb)β(3) inside-out signals and NF-κB activation in human platelets
por: Huang, Wei-Chieh, et al.
Publicado: (2023) -
Suppression of Human Platelet Activation via Integrin α(IIb)β(3) Outside-In Independent Signal and Reduction of the Mortality in Pulmonary Thrombosis by Auraptene
por: Hsia, Chih-Wei, et al.
Publicado: (2019) -
Auraptene, a Monoterpene Coumarin, Inhibits LTA-Induced Inflammatory Mediators via Modulating NF-κB/MAPKs Signaling Pathways
por: Hsia, Chih-Hsuan, et al.
Publicado: (2021) -
Corrigendum to “Auraptene, a Monoterpene Coumarin, Inhibits LTA-Induced Inflammatory Mediators via Modulating NF-κB/MAPKs Signaling Pathways”
por: Hsia, Chih-Hsuan, et al.
Publicado: (2022)