Cargando…

Genetic Labeling of Cells Allows Identification and Tracking of Transgenic Platelets in Mice

Background: The use of knock-out mouse models is crucial to understand platelet activation and aggregation. Methods: Analysis of the global double fluorescent Cre reporter mouse mT/mG that has been crossbred with the megakaryocyte/platelet specific PF4-Cre mouse. Results: Platelets show bright mT (P...

Descripción completa

Detalles Bibliográficos
Autores principales:	Krüger, Irena, Reusswig, Friedrich, Krott, Kim Jürgen, Lersch, Celina Fabienne, Spelleken, Martina, Elvers, Margitta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037568/ https://www.ncbi.nlm.nih.gov/pubmed/33918229 http://dx.doi.org/10.3390/ijms22073710

Ejemplares similares

Phospholipase D1 regulation of TNF-alpha protects against responses to LPS
por: Urbahn, Marc-Andre, et al.
Publicado: (2018)

The NMDA receptor regulates integrin activation, ATP release and arterial thrombosis through store-operated Ca(2+) entry in platelets
por: Reusswig, Friedrich, et al.
Publicado: (2023)

Molecular Drivers of Platelet Activation: Unraveling Novel Targets for Anti-Thrombotic and Anti-Thrombo-Inflammatory Therapy
por: Chatterjee, Madhumita, et al.
Publicado: (2020)

The Proteoglycan Biglycan Modulates Platelet Adhesion and Thrombus Formation in a GPVI-Dependent Manner
por: Hoermann, Henrike, et al.
Publicado: (2021)

Only Acute but Not Chronic Thrombocytopenia Protects Mice against Left Ventricular Dysfunction after Acute Myocardial Infarction
por: Reusswig, Friedrich, et al.
Publicado: (2022)

Efficiently Restored Thrombopoietin Production by Ashwell‐Morell Receptor and IL‐6R Induced Janus Kinase 2/Signal Transducer and Activator of Transcription Signaling Early After Partial Hepatectomy
por: Reusswig, Friedrich, et al.
Publicado: (2021)

Platelet pannexin-1 channels modulate neutrophil activation and migration but not the progression of abdominal aortic aneurysm
por: Metz, Lisa Maria, et al.
Publicado: (2023)

Pannexin-1 Activation by Phosphorylation Is Crucial for Platelet Aggregation and Thrombus Formation
por: Metz, Lisa Maria, et al.
Publicado: (2022)

Enhanced Integrin Activation of PLD2-Deficient Platelets Accelerates Inflammation after Myocardial Infarction
por: Klose, Aglaia Maria, et al.
Publicado: (2020)

Impact of Amyloid-β on Platelet Mitochondrial Function and Platelet–Mediated Amyloid Aggregation in Alzheimer’s Disease
por: Donner, Lili, et al.
Publicado: (2021)

Dapagliflozin reduces thrombin generation and platelet activation: implications for cardiovascular risk reduction in type 2 diabetes mellitus
por: Kohlmorgen, Christina, et al.
Publicado: (2021)

Minimal Collagen-Binding Epitope of Glycoprotein VI in Human and Mouse Platelets
por: Han, Chao, et al.
Publicado: (2023)

Ethanol Enhances Endothelial Rigidity by Targeting VE-Cadherin—Implications for Acute Aortic Dissection
por: Mulorz, Joscha, et al.
Publicado: (2023)

Blood Platelets in the Progression of Alzheimer’s Disease
por: Gowert, Nina S., et al.
Publicado: (2014)

The Sox2 promoter-driven CD63-GFP transgenic rat model allows tracking of neural stem cell-derived extracellular vesicles
por: Yoshimura, Aya, et al.
Publicado: (2018)

Highly efficient magnetic labelling allows MRI tracking of the homing of stem cell‐derived extracellular vesicles following systemic delivery
por: Han, Zheng, et al.
Publicado: (2021)

Tumor necrosis factor α triggers proliferation of adult neural stem cells via IKK/NF-κB signaling
por: Widera, Darius, et al.
Publicado: (2006)

Tumor necrosis factor alpha induced proliferation of adult neural stem cells is mediated via NF-κB
por: Widera, Darius, et al.
Publicado: (2007)

Coloring coral larvae allows tracking of local dispersal and settlement
por: Doropoulos, Christopher, et al.
Publicado: (2022)

Hierarchically Labeled Database Indexing Allows Scalable Characterization of Microbiomes
por: Utro, Filippo, et al.
Publicado: (2020)

Anti-TNF-α antibody allows healing of joint damage in polyarthritic transgenic mice
por: Shealy, David J, et al.
Publicado: (2002)

Intestinal transgene delivery with native E. coli chassis allows persistent physiological changes
por: Russell, Baylee J., et al.
Publicado: (2022)

Track labelling by ultrasound inside bubble chambers: internal picket fence
por: Hilke, Hans Jürgen
Publicado: (1979)

Magnet tracking allows assessment of regional gastrointestinal transit times in children
por: Hedsund, Caroline, et al.
Publicado: (2013)

Spread spectrum SERS allows label-free detection of attomolar neurotransmitters
por: Lee, Wonkyoung, et al.
Publicado: (2021)

The Effect of Perioperative Auditory Stimulation with Music on Procedural Pain: A Narrative Review
por: Frickmann, Fabienne C. S., et al.
Publicado: (2023)

Cre reconstitution allows for DNA recombination selectively in dual-marker-expressing cells in transgenic mice
por: Xu, Yanwen, et al.
Publicado: (2007)

Snca-GFP Knock-In Mice Allows Tracking the Endogenous α-Synuclein in Action
por: Er, Safak
Publicado: (2021)

Intelligent wearable allows out-of-the-lab tracking of developing motor abilities in infants
por: Airaksinen, Manu, et al.
Publicado: (2022)

Puromycin labeling does not allow protein synthesis to be measured in energy-starved cells
por: Marciano, Ran, et al.
Publicado: (2018)

Varying label density allows artifact-free analysis of membrane-protein nanoclusters
por: Baumgart, Florian, et al.
Publicado: (2016)

Metabolic labeling in middle-down proteomics allows for investigation of the dynamics of the histone code
por: Sidoli, Simone, et al.
Publicado: (2017)

CRISPR-Cas9 Mediated Labelling Allows for Single Molecule Imaging and Resolution
por: Khan, Abdullah O., et al.
Publicado: (2017)

Molecular Imaging of Activated Platelets Allows the Detection of Pulmonary Embolism with Magnetic Resonance Imaging
por: Heidt, Timo, et al.
Publicado: (2016)

Reduced Heterochromatin Formation on the pFAR4 Miniplasmid Allows Sustained Transgene Expression in the Mouse Liver
por: Pastor, Marie, et al.
Publicado: (2020)

Transgenic expression of Nix converts genetic females into males and allows automated sex sorting in Aedes albopictus
por: Lutrat, Célia, et al.
Publicado: (2022)

Transgenic tools for targeted chromosome rearrangements allow construction of balancer chromosomes in non-melanogaster Drosophila species
por: Stern, David L
Publicado: (2022)

Combining two genetic sexing strains allows sorting of non-transgenic males for Aedes genetic control
por: Lutrat, Célia, et al.
Publicado: (2023)

Evaluation of adenovirus capsid labeling versus transgene expression
por: Li, Jing, et al.
Publicado: (2010)

Single cell biomass tracking allows identification and isolation of rare targeted therapy-resistant DLBCL cells within a mixed population
por: Murray, Graeme F., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_otp2hb41lpii54sjhva64krub9