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High Seroprevalence of SARS-CoV-2 among Healthcare Workers in a North Italy Hospital
Background: Healthcare workers (HCWs) have been the key players in the fight against the coronavirus disease 2019 (COVID-19) pandemic. The aim of our study was to evaluate the seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) IgG anti-bodies. Methods: We conducted a cros...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037577/ https://www.ncbi.nlm.nih.gov/pubmed/33804893 http://dx.doi.org/10.3390/ijerph18073343 |
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author | Airoldi, Chiara Patrucco, Filippo Milano, Fulvia Alessi, Daniela Sarro, Andrea Rossi, Maicol Andrea Cena, Tiziana Borrè, Silvio Faggiano, Fabrizio |
author_facet | Airoldi, Chiara Patrucco, Filippo Milano, Fulvia Alessi, Daniela Sarro, Andrea Rossi, Maicol Andrea Cena, Tiziana Borrè, Silvio Faggiano, Fabrizio |
author_sort | Airoldi, Chiara |
collection | PubMed |
description | Background: Healthcare workers (HCWs) have been the key players in the fight against the coronavirus disease 2019 (COVID-19) pandemic. The aim of our study was to evaluate the seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) IgG anti-bodies. Methods: We conducted a cross-sectional study among workers of two hospitals and Territorial Medical and Administrative services in Northern Italy. From 8 May to 3 June 2020, 2252 subjects were tested. Seroprevalence and 95% confidence interval (CI) were calculated for all individuals who were stratified by job title, COVID-19 risk of exposure, direct contact with patients, unit ward, and intensity of care. Results: Median age was 50 years, and 72% of subjects were female. The overall seroprevalence was 17.11% [95% CI 15.55–18.67]. Around 20% of healthcare assistants were seropositive, followed by physicians and nurses (16.89% and 15.84%, respectively). HCWs with high risk of exposure to COVID-19 were more frequently seropositive (28.52%) with respect to those with medium and low risks (16.71% and 12.76%, respectively). Moreover, personnel in direct contact had higher prevalence (18.32%) compared to those who did not (10.66%). Furthermore, the IgG were more frequently detected among personnel of one hospital (19.43%). Conclusion: The high seroprevalence observed can be partially explained by the timing and the population seroprevalence; the study was conducted in an area with huge spread of the infection. |
format | Online Article Text |
id | pubmed-8037577 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-80375772021-04-12 High Seroprevalence of SARS-CoV-2 among Healthcare Workers in a North Italy Hospital Airoldi, Chiara Patrucco, Filippo Milano, Fulvia Alessi, Daniela Sarro, Andrea Rossi, Maicol Andrea Cena, Tiziana Borrè, Silvio Faggiano, Fabrizio Int J Environ Res Public Health Article Background: Healthcare workers (HCWs) have been the key players in the fight against the coronavirus disease 2019 (COVID-19) pandemic. The aim of our study was to evaluate the seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) IgG anti-bodies. Methods: We conducted a cross-sectional study among workers of two hospitals and Territorial Medical and Administrative services in Northern Italy. From 8 May to 3 June 2020, 2252 subjects were tested. Seroprevalence and 95% confidence interval (CI) were calculated for all individuals who were stratified by job title, COVID-19 risk of exposure, direct contact with patients, unit ward, and intensity of care. Results: Median age was 50 years, and 72% of subjects were female. The overall seroprevalence was 17.11% [95% CI 15.55–18.67]. Around 20% of healthcare assistants were seropositive, followed by physicians and nurses (16.89% and 15.84%, respectively). HCWs with high risk of exposure to COVID-19 were more frequently seropositive (28.52%) with respect to those with medium and low risks (16.71% and 12.76%, respectively). Moreover, personnel in direct contact had higher prevalence (18.32%) compared to those who did not (10.66%). Furthermore, the IgG were more frequently detected among personnel of one hospital (19.43%). Conclusion: The high seroprevalence observed can be partially explained by the timing and the population seroprevalence; the study was conducted in an area with huge spread of the infection. MDPI 2021-03-24 /pmc/articles/PMC8037577/ /pubmed/33804893 http://dx.doi.org/10.3390/ijerph18073343 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ). |
spellingShingle | Article Airoldi, Chiara Patrucco, Filippo Milano, Fulvia Alessi, Daniela Sarro, Andrea Rossi, Maicol Andrea Cena, Tiziana Borrè, Silvio Faggiano, Fabrizio High Seroprevalence of SARS-CoV-2 among Healthcare Workers in a North Italy Hospital |
title | High Seroprevalence of SARS-CoV-2 among Healthcare Workers in a North Italy Hospital |
title_full | High Seroprevalence of SARS-CoV-2 among Healthcare Workers in a North Italy Hospital |
title_fullStr | High Seroprevalence of SARS-CoV-2 among Healthcare Workers in a North Italy Hospital |
title_full_unstemmed | High Seroprevalence of SARS-CoV-2 among Healthcare Workers in a North Italy Hospital |
title_short | High Seroprevalence of SARS-CoV-2 among Healthcare Workers in a North Italy Hospital |
title_sort | high seroprevalence of sars-cov-2 among healthcare workers in a north italy hospital |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037577/ https://www.ncbi.nlm.nih.gov/pubmed/33804893 http://dx.doi.org/10.3390/ijerph18073343 |
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