Cargando…

High Seroprevalence of SARS-CoV-2 among Healthcare Workers in a North Italy Hospital

Background: Healthcare workers (HCWs) have been the key players in the fight against the coronavirus disease 2019 (COVID-19) pandemic. The aim of our study was to evaluate the seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) IgG anti-bodies. Methods: We conducted a cros...

Descripción completa

Detalles Bibliográficos
Autores principales: Airoldi, Chiara, Patrucco, Filippo, Milano, Fulvia, Alessi, Daniela, Sarro, Andrea, Rossi, Maicol Andrea, Cena, Tiziana, Borrè, Silvio, Faggiano, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037577/
https://www.ncbi.nlm.nih.gov/pubmed/33804893
http://dx.doi.org/10.3390/ijerph18073343
_version_ 1783677176295456768
author Airoldi, Chiara
Patrucco, Filippo
Milano, Fulvia
Alessi, Daniela
Sarro, Andrea
Rossi, Maicol Andrea
Cena, Tiziana
Borrè, Silvio
Faggiano, Fabrizio
author_facet Airoldi, Chiara
Patrucco, Filippo
Milano, Fulvia
Alessi, Daniela
Sarro, Andrea
Rossi, Maicol Andrea
Cena, Tiziana
Borrè, Silvio
Faggiano, Fabrizio
author_sort Airoldi, Chiara
collection PubMed
description Background: Healthcare workers (HCWs) have been the key players in the fight against the coronavirus disease 2019 (COVID-19) pandemic. The aim of our study was to evaluate the seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) IgG anti-bodies. Methods: We conducted a cross-sectional study among workers of two hospitals and Territorial Medical and Administrative services in Northern Italy. From 8 May to 3 June 2020, 2252 subjects were tested. Seroprevalence and 95% confidence interval (CI) were calculated for all individuals who were stratified by job title, COVID-19 risk of exposure, direct contact with patients, unit ward, and intensity of care. Results: Median age was 50 years, and 72% of subjects were female. The overall seroprevalence was 17.11% [95% CI 15.55–18.67]. Around 20% of healthcare assistants were seropositive, followed by physicians and nurses (16.89% and 15.84%, respectively). HCWs with high risk of exposure to COVID-19 were more frequently seropositive (28.52%) with respect to those with medium and low risks (16.71% and 12.76%, respectively). Moreover, personnel in direct contact had higher prevalence (18.32%) compared to those who did not (10.66%). Furthermore, the IgG were more frequently detected among personnel of one hospital (19.43%). Conclusion: The high seroprevalence observed can be partially explained by the timing and the population seroprevalence; the study was conducted in an area with huge spread of the infection.
format Online
Article
Text
id pubmed-8037577
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-80375772021-04-12 High Seroprevalence of SARS-CoV-2 among Healthcare Workers in a North Italy Hospital Airoldi, Chiara Patrucco, Filippo Milano, Fulvia Alessi, Daniela Sarro, Andrea Rossi, Maicol Andrea Cena, Tiziana Borrè, Silvio Faggiano, Fabrizio Int J Environ Res Public Health Article Background: Healthcare workers (HCWs) have been the key players in the fight against the coronavirus disease 2019 (COVID-19) pandemic. The aim of our study was to evaluate the seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) IgG anti-bodies. Methods: We conducted a cross-sectional study among workers of two hospitals and Territorial Medical and Administrative services in Northern Italy. From 8 May to 3 June 2020, 2252 subjects were tested. Seroprevalence and 95% confidence interval (CI) were calculated for all individuals who were stratified by job title, COVID-19 risk of exposure, direct contact with patients, unit ward, and intensity of care. Results: Median age was 50 years, and 72% of subjects were female. The overall seroprevalence was 17.11% [95% CI 15.55–18.67]. Around 20% of healthcare assistants were seropositive, followed by physicians and nurses (16.89% and 15.84%, respectively). HCWs with high risk of exposure to COVID-19 were more frequently seropositive (28.52%) with respect to those with medium and low risks (16.71% and 12.76%, respectively). Moreover, personnel in direct contact had higher prevalence (18.32%) compared to those who did not (10.66%). Furthermore, the IgG were more frequently detected among personnel of one hospital (19.43%). Conclusion: The high seroprevalence observed can be partially explained by the timing and the population seroprevalence; the study was conducted in an area with huge spread of the infection. MDPI 2021-03-24 /pmc/articles/PMC8037577/ /pubmed/33804893 http://dx.doi.org/10.3390/ijerph18073343 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Article
Airoldi, Chiara
Patrucco, Filippo
Milano, Fulvia
Alessi, Daniela
Sarro, Andrea
Rossi, Maicol Andrea
Cena, Tiziana
Borrè, Silvio
Faggiano, Fabrizio
High Seroprevalence of SARS-CoV-2 among Healthcare Workers in a North Italy Hospital
title High Seroprevalence of SARS-CoV-2 among Healthcare Workers in a North Italy Hospital
title_full High Seroprevalence of SARS-CoV-2 among Healthcare Workers in a North Italy Hospital
title_fullStr High Seroprevalence of SARS-CoV-2 among Healthcare Workers in a North Italy Hospital
title_full_unstemmed High Seroprevalence of SARS-CoV-2 among Healthcare Workers in a North Italy Hospital
title_short High Seroprevalence of SARS-CoV-2 among Healthcare Workers in a North Italy Hospital
title_sort high seroprevalence of sars-cov-2 among healthcare workers in a north italy hospital
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037577/
https://www.ncbi.nlm.nih.gov/pubmed/33804893
http://dx.doi.org/10.3390/ijerph18073343
work_keys_str_mv AT airoldichiara highseroprevalenceofsarscov2amonghealthcareworkersinanorthitalyhospital
AT patruccofilippo highseroprevalenceofsarscov2amonghealthcareworkersinanorthitalyhospital
AT milanofulvia highseroprevalenceofsarscov2amonghealthcareworkersinanorthitalyhospital
AT alessidaniela highseroprevalenceofsarscov2amonghealthcareworkersinanorthitalyhospital
AT sarroandrea highseroprevalenceofsarscov2amonghealthcareworkersinanorthitalyhospital
AT rossimaicolandrea highseroprevalenceofsarscov2amonghealthcareworkersinanorthitalyhospital
AT cenatiziana highseroprevalenceofsarscov2amonghealthcareworkersinanorthitalyhospital
AT borresilvio highseroprevalenceofsarscov2amonghealthcareworkersinanorthitalyhospital
AT faggianofabrizio highseroprevalenceofsarscov2amonghealthcareworkersinanorthitalyhospital