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Honokiol Prevents Non-Alcoholic Steatohepatitis-Induced Liver Cancer via EGFR Degradation through the Glucocorticoid Receptor—MIG6 Axis
SIMPLE SUMMARY: Non-alcoholic fatty liver disease (NAFLD) is a major health problem globally linked with the growing prevalence of metabolic syndrome. A subset of patients with NAFLD progress to non-alcoholic steatohepatitis (NASH), which increases the risk of hepatocellular carcinoma (HCC). However...
Autores principales: | Okuda, Keiichiro, Umemura, Atsushi, Umemura, Shiori, Kataoka, Seita, Taketani, Hiroyoshi, Seko, Yuya, Nishikawa, Taichiro, Yamaguchi, Kanji, Moriguchi, Michihisa, Kanbara, Yoshihiro, Arbiser, Jack L., Shima, Toshihide, Okanoue, Takeshi, Karin, Michael, Itoh, Yoshito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037653/ https://www.ncbi.nlm.nih.gov/pubmed/33806040 http://dx.doi.org/10.3390/cancers13071515 |
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